Agmatine attenuates rhabdomyolysis-induced acute kidney injury in rats in a dose dependent manner
Acute kidney injury (AKI) is a serious disorder that accompanies rhabdomyolysis (RM). The
underlying mechanisms as well as protective approaches need to be investigated. This …
underlying mechanisms as well as protective approaches need to be investigated. This …
Agmatine improves renal function in gentamicin-induced nephrotoxicity in rats
DH El-Kashef, AE El-Kenawi, MA Rahim… - Canadian Journal of …, 2016 - cdnsciencepub.com
The present study was designed to explore the possible protective effects of agmatine, a
known nitric oxide (NO) synthase inhibitor, against gentamicin-induced nephrotoxicity in …
known nitric oxide (NO) synthase inhibitor, against gentamicin-induced nephrotoxicity in …
Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin …
Rhabdomyolysis induced acute kidney injury (RIAKI) is a life-threatening condition
responsible for approximately 19-58% of AKI cases worldwide. We performed an …
responsible for approximately 19-58% of AKI cases worldwide. We performed an …
Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options
Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …
Fasudil ameliorates rhabdomyolysis-induced acute kidney injury via inhibition of apoptosis
During times of war or natural disasters, rhabdomyolysis leading to acute kidney injury (AKI)
can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI …
can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI …
Protective effect of naringin, a bioflavonoid on glycerol-induced acute renal failure in rat kidney
D Singh, V Chander, K Chopra - Toxicology, 2004 - Elsevier
Rhabdomyolysis-induced myoglobinuric acute renal failure accounts for about 10–40% of
all cases of acute renal failure (ARF). Reactive oxygen intermediates have been …
all cases of acute renal failure (ARF). Reactive oxygen intermediates have been …
Alamandine protects against renal ischaemia–reperfusion injury in rats via inhibiting oxidative stress
J Zhu, JG Qiu, WT Xu, HX Ma… - Journal of Pharmacy and …, 2021 - academic.oup.com
Objective This study was to determine whether alamandine (Ala) could reduce ischaemia
and reperfusion (I/R) injury of kidney in rats. Methods Renal I/R was induced by an occlusion …
and reperfusion (I/R) injury of kidney in rats. Methods Renal I/R was induced by an occlusion …
Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated …
L Al-Kharashi, H Attia, A Alsaffi, T Almasri… - Toxicology and Applied …, 2023 - Elsevier
Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …
Angiotensin 1–7 mitigates rhabdomyolysis induced renal injury in rats via modulation of TLR-4/NF-kB/iNOS and Nrf-2/heme‑oxygenase-1 signaling pathways
EA Abdel-Hakeem, SMNA Hafez, BA Kamel… - Life Sciences, 2022 - Elsevier
Aims Rhabdomyolysis (RM) is a critical condition with a high mortality rate, but effective
management is still deficient. Till date, there are no studies that have addressed the effect of …
management is still deficient. Till date, there are no studies that have addressed the effect of …
Loganetin protects against rhabdomyolysis‐induced acute kidney injury by modulating the toll‐like receptor 4 signalling pathway
J Li, Y Tan, M Wang, Y Sun, G Li… - British Journal of …, 2019 - Wiley Online Library
Background and Purpose Acute kidney injury (AKI) is a rapid renal dysfunctional disease, for
which no effective drugs or therapies are available to improve prognosis. Loganetin is a …
which no effective drugs or therapies are available to improve prognosis. Loganetin is a …