Acute kidney injury (AKI) is a serious disorder that accompanies rhabdomyolysis (RM). The
underlying mechanisms as well as protective approaches need to be investigated. This …

The present study was designed to explore the possible protective effects of agmatine, a
known nitric oxide (NO) synthase inhibitor, against gentamicin-induced nephrotoxicity in …

Rhabdomyolysis induced acute kidney injury (RIAKI) is a life-threatening condition
responsible for approximately 19-58% of AKI cases worldwide. We performed an …

Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …

During times of war or natural disasters, rhabdomyolysis leading to acute kidney injury (AKI)
can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI …

Rhabdomyolysis-induced myoglobinuric acute renal failure accounts for about 10–40% of
all cases of acute renal failure (ARF). Reactive oxygen intermediates have been …

Objective This study was to determine whether alamandine (Ala) could reduce ischaemia
and reperfusion (I/R) injury of kidney in rats. Methods Renal I/R was induced by an occlusion …

Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

Aims Rhabdomyolysis (RM) is a critical condition with a high mortality rate, but effective
management is still deficient. Till date, there are no studies that have addressed the effect of …

Background and Purpose Acute kidney injury (AKI) is a rapid renal dysfunctional disease, for
which no effective drugs or therapies are available to improve prognosis. Loganetin is a …