Background Safe and effective treatments are required for patients with ulcerative colitis. It
was suggested that granulocyte and monocyte adsorption apheresis might play an important …

Recent studies suggest that leukocytapheresis with Cellsorba is a valuable therapy for
ulcerative colitis after failure of conventional treatment. In this study the potential of …

Abstract Background Active Crohn's disease (CD) is often associated with elevated levels of
platelets, granulocytes, and monocytes that are activated and resistant to apoptosis. The …

Aliment Pharmacol Ther 2010; 32: 1297–1306 Summary Background Patients with
ulcerative colitis (UC) that is chronically active despite 5‐aminosalicylates or …

AIM: To study the efficacy, safety, and feasibility of a granulocyte adsorptive type apheresis
system for the treatment of patients with chronically active ulcerative colitis despite standard …

BACKGROUND/AIM: The Adacolumn selectively depletes granulocytes and monocytes/
macrophages, which are thought to be part of the immunopathogenesis of ulcerative colitis …

Background/Aim: Active ulcerative colitis (UC) is often associated with increased peripheral
granulocytes and monocytes/macrophages which show activation behavior and prolonged …

Background This prospective study assessed the impact of selective leukocytapheresis
(SLA) on mucosal inflammation in patients with active ulcerative colitis (UC) by endoscopic …

Chemotactic, phagocytic, and oxidative metabolic activity of exudative leukocytes was
measured in patients with Crohn's disease (n= 20) and with ulcerative colitis (n= 20) …

In patients with inflammatory bowel disease (IBD), centrifugation has been attempted to
remove leukocyte components from whole blood; however, the use of selective filters has …