Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking, molecular …
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
Rutin and flavone analogs as prospective SARS-CoV-2 main protease inhibitors: In silico drug discovery study
MAA Ibrahim, EAR Mohamed… - Journal of Molecular …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a new pandemic characterized by quick
spreading and illness of the respiratory system. To date, there is no specific therapy for …
spreading and illness of the respiratory system. To date, there is no specific therapy for …
Anthocyanin derivatives as potent inhibitors of SARS-CoV-2 main protease: An in-silico perspective of therapeutic targets against COVID-19 pandemic
Z Fakhar, B Faramarzi, S Pacifico… - Journal of Biomolecular …, 2021 - Taylor & Francis
A new pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
spread worldwide and become pandemic with thousands new deaths and infected cases …
spread worldwide and become pandemic with thousands new deaths and infected cases …
Synthetic flavonoids as potential antiviral agents against SARS-CoV-2 main protease
The COVID-19 pandemic has claimed more than a million lives worldwide within a short
time span. Due to the unavailability of specific antiviral drugs or vaccine, the infections are …
time span. Due to the unavailability of specific antiviral drugs or vaccine, the infections are …
Potential bioactive glycosylated flavonoids as SARS-CoV-2 main protease inhibitors: A molecular docking and simulation studies
SA Cherrak, H Merzouk, N Mokhtari-Soulimane - Plos one, 2020 - journals.plos.org
A novel coronavirus responsible of acute respiratory infection closely related to SARS-CoV
has recently emerged. So far there is no consensus for drug treatment to stop the spread of …
has recently emerged. So far there is no consensus for drug treatment to stop the spread of …
Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (Mpro) inhibitors to unveil a hope against COVID-19
Abstract SARS-CoV-2, a rapidly spreading new strain of human coronavirus, has affected
almost all the countries around the world. The lack of specific drugs against SARS-CoV-2 is …
almost all the countries around the world. The lack of specific drugs against SARS-CoV-2 is …
Identification of antiviral phytochemicals as a potential SARS-CoV-2 main protease (Mpro) inhibitor using docking and molecular dynamics simulations
Abstract Novel SARS-CoV-2, an etiological factor of Coronavirus disease 2019 (COVID-19),
poses a great challenge to the public health care system. Among other druggable targets of …
poses a great challenge to the public health care system. Among other druggable targets of …
Protease inhibitory effect of natural polyphenolic compounds on SARS-CoV-2: an in silico study
The current pandemic, caused by SARS-CoV-2 virus, is a severe challenge for human
health and the world economy. There is an urgent need for development of drugs that can …
health and the world economy. There is an urgent need for development of drugs that can …
[HTML][HTML] Molecular docking, validation, dynamics simulations, and pharmacokinetic prediction of natural compounds against the SARS-CoV-2 main-protease
C Shivanika, D Kumar, V Ragunathan… - … structure & dynamics, 2020 - ncbi.nlm.nih.gov
The study aims to evaluate the potency of two hundred natural antiviral phytocompounds
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
In silico screening of phytopolyphenolics for the identification of bioactive compounds as novel protease inhibitors effective against SARS-CoV-2
M Rudrapal, AR Issahaku, C Agoni… - Journal of …, 2022 - Taylor & Francis
Due to the unavailability specific drugs or vaccines (FDA approved) that can cure COVID-19,
the development of potent antiviral drug candidates/therapeutic molecules against COVID …
the development of potent antiviral drug candidates/therapeutic molecules against COVID …