Association of the miR-196a2, miR-146a, and miR-499 polymorphisms with asthma phenotypes in a Korean population

HKT Trinh, DL Pham, SC Kim, RY Kim, HS Park… - Molecular Diagnosis & …, 2017 - Springer
Background MicroRNAs (miRNAs) modulate expressions of inflammatory genes, thereby
regulating inflammatory responses. Single nucleotide polymorphisms (SNPs) in miRNAs …

Association of two polymorphisms of miRNA-146a rs2910164 (G> C) and miRNA-499 rs3746444 (T> C) with asthma: a meta-analysis

J Dong, D Sun, F Lu - Journal of Asthma, 2021 - Taylor & Francis
Objective To conduct a meta-analysis to determine the association between two single
nucleotide polymorphisms (SNPs) miRNA146a rs2910164 (G> C) and miRNA-499 …

Genetic variants in miR-145 gene are associated with the risk of asthma in Taiwan

SC Wang, CW Tsai, WS Chang, NY Hsia, MC Mong… - Scientific reports, 2022 - nature.com
Asthma is a chronic airway inflammation disease and the diagnosis and treatment strategies
remain difficult. MicroRNAs play important roles in many biological and pathological …

A passenger strand variant in miR-196a2 contributes to asthma severity in children and adolescents: A preliminary study

MH Hussein, EA Toraih, NM Aly, E Riad… - Biochemistry and Cell …, 2016 - cdnsciencepub.com
There is emerging evidence to support the role of microRNAs in allergic airway diseases
and inflammation. Genetic variants in microRNA genes might affect microRNA-mediated cell …

Asthma inflammatory phenotypes show differential microRNA expression in sputum

T Maes, FA Cobos, F Schleich, V Sorbello… - Journal of Allergy and …, 2016 - Elsevier
Background Asthma is classified according to severity and inflammatory phenotype and is
likely to be distinguished by specific microRNA (miRNA) expression profiles. Objective We …

[PDF][PDF] Single nucleotide polymorphisms in the promoter region of mir-133a-1 and in pre-mir-152 rs1707 may contribute to the risk of asthma in a Chinese Han …

PP Zhou, Y Li, ZD Ma, ZY Li, FY Chen… - European Review for …, 2016 - europeanreview.org
Han population (p< 0.001). However, the genotype and allele frequencies of rs5186, located
in pre-miR-155, did not significantly differ between the cases and the controls; as well as …

Serum microRNAs Catalog Asthma Patients by Phenotype.

M Gil-Martínez, JM Rodrigo-Muñoz… - … Allergology & Clinical …, 2022 - europepmc.org
Methods Serum miRNAs of patients with eosinophilic asthma (N= 40) and patients with
noneosinophilic asthma (N= 36) were evaluated using next-generation sequencing …

Identification of asthma-associated microRNAs in bronchial biopsies

MP Roffel, IM Boudewijn… - European …, 2022 - Eur Respiratory Soc
Background Changes in microRNA (miRNA) expression can contribute to the pathogenesis
of many diseases, including asthma. We aimed to identify miRNAs that are differentially …

Circulating microRNAs correlate to clinical parameters in individuals with allergic and non-allergic asthma

J Weidner, L Ekerljung, C Malmhäll, N Miron… - Respiratory …, 2020 - Springer
Background Asthma is a chronic airway disease affecting millions of people. Better methods
to define asthma subgroups using clinical parameters and molecular biomarkers are crucial …

Circulating microRNAs and T-cell cytokine expression are associated with the characteristics of asthma exacerbation

A Wardzyńska, M Pawełczyk… - Allergy, Asthma & …, 2020 - synapse.koreamed.org
Purpose Immunological mechanisms underlying asthma exacerbation have not been
elucidated. The aim of this study was to assess the associations of various asthma …