During pregnancy, reactive oxygen species (ROS) serve as crucial signaling molecules for
fetoplacental circulatory physiology. Oxidative stress is thought to sustain the pathogenesis …

Oxidative stress (OS) occurs at birth in all newborns as a consequence of the hyperoxic
challenge due to the transition from the hypoxic intrauterine environment to extrauterine life …

Aim: The purpose of the present study was to examine the effect of lipopolysaccharide (LPS)
and intermittent hypoxia–ischemia (HI) on brain damage in neonatal rats. Methods: Seven …

Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of morbidity and
mortality in neonates. Because of high concentrations of sensitive immature cells, metal …

Hypoxic injury in the fetal and neonatal brain results in neonatal mortality and morbidity and
long-term sequelae such as cerebral palsy, mental retardation, epilepsy, and learning …

The prevalence of cerebral palsy (CP) shows little temporal or geographic variation and is
associated with preterm birth, maternal/fetal infection/inflammation, and fetal growth …

Use of maternal oxygen for intrauterine resuscitation is contentious because of the lack of
evidence for its efficacy and the possibility of fetal harm through oxidative stress. Because …

Neonatal hypoxic ischemic encephalopathy has a highly complex pathogenesis. Despite
advances it is one of the leading cause of neonatal mortality. The aim of this study was to …

The pathogenesis of cerebral ischemia–reperfusion (I/R) injury is complex and does not
exhibit an effective strategy. Maternal inflammation represents one of the most important …

OBJECTIVE:: The purpose of this study was to investigate the impact of chronic hypoxia on
the nitric oxide synthase isoenzymes in specific brain structures. STUDY DESIGN:: Time …