[HTML][HTML] Histone demethylase lysine demethylase 5B in development and cancer
M Han, W Xu, P Cheng, H Jin, X Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Histone methylation is one of the most important chromatin posttranslational modifications. It
has a range of influences on nuclear functions including epigenetic inheritance …
has a range of influences on nuclear functions including epigenetic inheritance …
Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
J Yoo, GW Kim, YH Jeon, JY Kim, SW Lee… - … & Molecular Medicine, 2022 - nature.com
Distinct epigenetic modifiers ensure coordinated control over genes that govern a myriad of
cellular processes. Growing evidence shows that dynamic regulation of histone methylation …
cellular processes. Growing evidence shows that dynamic regulation of histone methylation …
The diverse roles of histone demethylase KDM4B in normal and cancer development and progression
Z Wang, H Cai, E Zhao, H Cui - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Histone methylation status is an important process associated with cell growth, survival,
differentiation and gene expression in human diseases. As a member of the KDM4 family …
differentiation and gene expression in human diseases. As a member of the KDM4 family …
Lysine demethylase KDM6A in differentiation, development, and cancer
ABSTRACT Lysine demethylase 6A (KDM6A), also known as UTX, belongs to the KDM6
family of histone H3 lysine 27 (H3K27) demethylases, which also includes UTY and KDM6B …
family of histone H3 lysine 27 (H3K27) demethylases, which also includes UTY and KDM6B …
The role of the histone demethylase KDM4A in cancer
L Guerra-Calderas, R González-Barrios, LA Herrera… - Cancer genetics, 2015 - Elsevier
Histone posttranslational modifications are important components of epigenetic regulation.
One extensively studied modification is the methylation of lysine residues. These …
One extensively studied modification is the methylation of lysine residues. These …
[HTML][HTML] The critical role of histone lysine demethylase KDM2B in cancer
M Yan, X Yang, H Wang, Q Shao - American journal of …, 2018 - ncbi.nlm.nih.gov
The discovery of histone demethylases has revealed the dynamic nature of the regulation of
histone methylation. KDM2B is an important histone lysine demethylase that removes methyl …
histone methylation. KDM2B is an important histone lysine demethylase that removes methyl …
[HTML][HTML] Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential
RM Labbé, A Holowatyj, ZQ Yang - American journal of …, 2014 - ncbi.nlm.nih.gov
KDM4 histone demethylases catalyze the removal of methyl marks from histone lysine
residues to epigenetically regulate chromatin structure and gene expression. KDM4 …
residues to epigenetically regulate chromatin structure and gene expression. KDM4 …
KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer
Epigenetic regulation of chromatin plays a critical role in controlling stem cell function and
tumorigenesis. The histone lysine demethylase, KDM5B, which catalyzes the demethylation …
tumorigenesis. The histone lysine demethylase, KDM5B, which catalyzes the demethylation …
Advances in histone demethylase KDM4 as cancer therapeutic targets
DH Lee, GW Kim, YH Jeon, J Yoo, SW Lee… - The FASEB …, 2020 - Wiley Online Library
Abstract The KDM4 subfamily H3K9 histone demethylases are epigenetic regulators that
control chromatin structure and gene expression by demethylating histone H3K9, H3K36 …
control chromatin structure and gene expression by demethylating histone H3K9, H3K36 …
Advances in histone demethylase KDM3A as a cancer therapeutic target
J Yoo, YH Jeon, HY Cho, SW Lee, GW Kim, DH Lee… - Cancers, 2020 - mdpi.com
Lysine-specific histone demethylase 3 (KDM3) subfamily proteins are H3K9me2/me1
histone demethylases that promote gene expression. The KDM3 subfamily primarily consists …
histone demethylases that promote gene expression. The KDM3 subfamily primarily consists …