Frailty—A promising concept to evaluate disease vulnerability

AR Ribeiro, SE Howlett, A Fernandes - Mechanisms of Ageing and …, 2020 - Elsevier
With the emergence of diseases, people become frailer and are expected to be less tolerant
of adverse outcomes. Frailty was first described to explain the variability in life expectancy in …

[HTML][HTML] Frailty: a tale of two concepts

JD Walston, K Bandeen-Roche - BMC medicine, 2015 - Springer
Frailty is increasingly relevant for clinicians to improve care for vulnerable older adults.
Prominent frailty measures include the frailty phenotype and the frailty index. The frailty …

Hospital frailty risk score predicts outcomes in chronic obstructive pulmonary disease exacerbations

K Ushida, A Shimizu, S Hori, Y Yamamoto… - Archives of gerontology …, 2022 - Elsevier
Introduction Patients with chronic obstructive pulmonary disease (COPD) are at high risk for
frailty and prone to complications after admission for an acute exacerbation. We aim to …

[HTML][HTML] Causal relationship between frailty and chronic obstructive pulmonary disease or asthma: A two sample bidirectional Mendelian randomization study

J Qu, Y Liang, Y Rao, Y Pei, D Li, Y Zhang… - Archives of gerontology …, 2024 - Elsevier
Background Observational studies have established a strong association between frailty
and obstructive lung diseases. However, the causal nature of this association remains …

Physical activity as a predictor of absence of frailty in subjects with stable COPD and COPD exacerbation

MC Valenza, I Torres-Sánchez, I Cabrera-Martos… - Respiratory …, 2016 - rc.rcjournal.com
BACKGROUND: Frailty is a key issue in the care of elderly patients. Patients with COPD are
more likely to be frail, with a prevalence of 57.8%. Frailty is associated with a low level of …

Differences in characteristics between physical frailty assessments in chronic obstructive pulmonary disease: a multicenter cross-sectional observational study

Y Tanaka, M Hanada, C Kitagawa… - … Journal of Chronic …, 2023 - Taylor & Francis
Purpose Assessment for frailty is important as it enables timely intervention to prevent or
delay poor prognosis in chronic obstructive pulmonary disease (COPD). The aims of this …

[HTML][HTML] Is frailty diagnosis important in patients with COPD? a narrative review of the literature

FJ Tarazona-Santabalbina, E Naval… - International Journal of …, 2023 - mdpi.com
Frailty is prevalent in older adults and is related to a worsening functionality, quality of life,
and health outcomes. Though there is an increasing interest in this field, the relationship …

[HTML][HTML] The association between frailty and survival in patients with pleural disease: a retrospective cohort study

E Barton, A Verduri, B Carter, J Hughes, J Hewitt… - BMC pulmonary …, 2024 - Springer
There are currently no data on the relationship between frailty and mortality in pleural
disease. Understanding the relationship between frailty and outcomes is increasingly …

Frailty: implications for clinical practice and public health

EO Hoogendijk, J Afilalo, KE Ensrud, P Kowal, G Onder… - The Lancet, 2019 - thelancet.com
Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

A frailty assessment tool to predict in-hospital mortality in patients with acute exacerbations of chronic obstructive pulmonary disease

JJ Gu, Q Liu, LJ Zheng - International journal of chronic obstructive …, 2021 - Taylor & Francis
Background The exacerbation of chronic obstructive pulmonary disease (AECOPD) is a
chronic, frequent, and life-threatening lung disease. In 2014, a frailty index (FI) based on …