Molecular analysis of apo (a) fragmentation in polygenic hypercholesterolemia: characterization of a new plasma fragment pattern

S Gonbert, B Saint-Jore, P Giral, C Doucet… - … , and vascular biology, 2001 - Am Heart Assoc
Hypercholesterolemia is frequently associated with elevated Lp (a) levels, an independent
risk factor for coronary, cerebrovascular, and peripheral vascular disease. A portion of …

Study of apo (a) length polymorphism and lipoprotein (a) concentrations in subjects with single or double apo (a) isoforms

M Alaoui, C Merle, R Garnotel, D Jolly, V Durlach… - 2003 - degruyter.com
Cardiovascular risk is associated with high lipoprotein (a)(Lp (a)) concentrations and low
molecular weight apolipoprotein (a)(apo (a)) isoforms. We studied the relationship between …

Polymorphism and peripheral levels of apolipoprotein (a) in polygenic hypercholesterolemia and combined hyperlipidemia

GX Shen, D Mymin, T Dembinski… - Clinical and …, 1995 - search.proquest.com
This study demonstrates that peripheral apolipoprotein (a)[apo (a)] levels are higher in
patients with polygenic hypercholesterolemia (PH) and combined hyperlipidemia (CH) than …

Lipoprotein (a) concentrations and phenotypes in controls and patients with hypercholesterolemia or hypertriglyceridemia

MM Ritter, HC Geiss, WO Richter, P Schwandt - Metabolism, 1994 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] concentrations are known to be stable under various dietary
and drug regimens. Little is known about the influence of hyperlipoproteinemia on Lp (a) …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

Partial characterization of lipoproteins containing apo [a] in human atherosclerotic lesions

HF Hoff, J O'Neil, A Yashiro - Journal of lipid research, 1993 - ASBMB
Previously we quantified the amounts of immunoreactive apo [a] found in human
atherosclerotic lesions extracted sequentially with phosphate-buffered saline (PBS) and …

Multi-modal expression of apolipoprotein (a) gene in vivo

A Ichinose, K Suzuki, N Takabatake… - Journal of atherosclerosis …, 1998 - jstage.jst.go.jp
The apolipoprotein (a)[apo (a)] gene encodes a protein component of lipoprotein (a)[Lp (a)]
whose plasma levels vary among individuals. To study the implications of Lp (a), we …

Urinary excretion of apo (a) fragments: role in apo (a) catabolism

KM Kostner, G Maurer, K Huber… - … , and vascular biology, 1996 - Am Heart Assoc
The biosynthesis and assembly of lipoprotein (a)[Lp (a)], a marker for atherosclerotic
disease, appears to be well understood. However, information is lacking concerning the …

Lp (a) concentration and apo (a) isoform size. Relation to the presence of coronary artery disease in familial hypercholesterolemia.

JF Bowden, PH Pritchard, JS Hill… - … and Thrombosis: A …, 1994 - Am Heart Assoc
We studied the relation between the concentration of lipoprotein (a)[Lp (a)] in plasma,
apolipoprotein (a)[apo (a)] phenotype, and the clinical expression of coronary artery disease …

Molecular basis for “null” lipoprotein (a) phenotypes and the influence of apolipoprotein (a) size on plasma lipoprotein (a) level in the baboon.

AL White, JE Hixson, DL Rainwater… - Journal of Biological …, 1994 - Elsevier
High plasma levels of lipoprotein (a)(Lp (a)) and its unique apolipoprotein, apo (a), are an
independent risk factor for cardiovascular disease. Plasma Lp (a) levels vary over a 1000 …