[HTML][HTML] Antiviral activities of plant-derived indole and β-carboline alkaloids against human and avian influenza viruses

A Hegazy, SH Mahmoud, YAMM Elshaier… - Scientific Reports, 2023 - nature.com
The persistent evolution of drug-resistant influenza strains represents a global concern. The
innovation of new treatment approaches through drug screening strategies and investigating …

Alkaloids as the natural anti-influenza virus agents: a systematic review

MT Moradi, A Karimi, Z Lorigooini - Toxin reviews, 2018 - Taylor & Francis
Alkaloids are a rich source of important chemical compounds which can be used for
development of new anti-influenza agents. In this systematic review, we focused on the …

[HTML][HTML] Development and effects of influenza antiviral drugs

H Yin, N Jiang, W Shi, X Chi, S Liu, JL Chen, S Wang - Molecules, 2021 - mdpi.com
Influenza virus is a highly contagious zoonotic respiratory disease that causes seasonal
outbreaks each year and unpredictable pandemics occasionally with high morbidity and …

[HTML][HTML] 3-Indoleacetonitrile is highly effective in treating influenza a virus infection in vitro and in vivo

X Zhao, L Zhao, Y Zhao, K Huang, W Gong, Y Yang… - Viruses, 2021 - mdpi.com
Influenza A viruses are serious zoonotic pathogens that continuously cause pandemics in
several animal hosts, including birds, pigs, and humans. Indole derivatives containing an …

In vitro and computational insights revealing the potential inhibitory effect of Tanshinone IIA against influenza A virus

D Elebeedy, I Badawy, AA Elmaaty, MM Saleh… - Computers in biology …, 2022 - Elsevier
Seasonal human influenza is a serious respiratory infection caused by influenza viruses that
can be found all over the world. Type A influenza is a contagious viral infection that, if left …

Discovery of berberine based derivatives as anti-influenza agent through blocking of neuraminidase

G Enkhtaivan, P Muthuraman, DH Kim… - Bioorganic & Medicinal …, 2017 - Elsevier
In this study, we investigated the antiviral activity of newly synthesized berberine derivatives
(BD) against influenza virus infection using several strains in in vitro and in silico. The CPE …

Robust Antiviral Activity of Santonica Flower Extract (Artemisia cina) against Avian and Human Influenza A Viruses: In Vitro and Chemoinformatic Studies

A Hegazy, I Mostafa, YAMM Elshaier, SH Mahmoud… - ACS …, 2022 - ACS Publications
The evolution of drug-resistant viral strains following natural acquisition of resistance
mutations is a major obstacle to antiviral therapy. Besides the improper prescription of the …

[HTML][HTML] The antihistamine drugs carbinoxamine maleate and chlorpheniramine maleate exhibit potent antiviral activity against a broad spectrum of influenza viruses

W Xu, S Xia, J Pu, Q Wang, P Li, L Lu… - Frontiers in …, 2018 - frontiersin.org
Influenza A viruses (IAV) comprise some of the most common infectious pathogens in
humans, and they cause significant mortality and morbidity in immunocompromised people …

Design, synthesis, and biological evaluation of itaconic acid derivatives as potential anti-influenza agents

B Sethy, CF Hsieh, TJ Lin, PY Hu… - Journal of medicinal …, 2019 - ACS Publications
Influenza A viruses (IAVs) have caused worldwide epidemics and pandemics by
reassortment and generation of drug-resistant mutants, which render antivirals and current …

[HTML][HTML] Substantial effect of phytochemical constituents against the pandemic disease influenza—a review

AB Devi, R Sarala - Future Journal of Pharmaceutical Sciences, 2021 - Springer
Background Influenza is an acute respiratory tract infection caused by the influenza virus.
Vaccination and antiviral drugs are the two methods opted to control the disease. Besides …