[HTML][HTML] Blood–brain barrier disruption and its involvement in neurodevelopmental and neurodegenerative disorders
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …
regulates the uptake of molecules and solutes from the blood. The relevance of the …
[HTML][HTML] Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders
The integrity of the blood–brain barrier (BBB) is essential for normal central nervous system
(CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the …
(CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the …
Basic physiology of the blood-brain barrier in health and disease: a brief overview
M Kaya, B Ahishali - Tissue Barriers, 2021 - Taylor & Francis
The blood-brain barrier (BBB), a dynamic interface between blood and brain constituted
mainly by endothelial cells of brain microvessels, robustly restricts the entry of potentially …
mainly by endothelial cells of brain microvessels, robustly restricts the entry of potentially …
Blood‐brain barrier overview: structural and functional correlation
A Alahmari - Neural plasticity, 2021 - Wiley Online Library
The blood‐brain barrier (BBB) is a semipermeable and extremely selective system in the
central nervous system of most vertebrates, that separates blood from the brain's …
central nervous system of most vertebrates, that separates blood from the brain's …
Development of novel therapeutics targeting the blood–brain barrier: from barrier to carrier
The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described
as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from …
as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from …
[HTML][HTML] The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
[HTML][HTML] Mechanistic insights, treatment paradigms, and clinical progress in neurological disorders: current and future prospects
Neurodegenerative diseases (NDs) are a major cause of disability and are related to brain
development. The neurological signs of brain lesions can vary from mild clinical shortfalls to …
development. The neurological signs of brain lesions can vary from mild clinical shortfalls to …
[HTML][HTML] Study of BBB dysregulation in neuropathogenicity using integrative human model of blood–brain barrier
C Simöes Da Gama, M Morin-Brureau - Frontiers in Cellular …, 2022 - frontiersin.org
The blood–brain barrier (BBB) is a cellular and physical barrier with a crucial role in
homeostasis of the brain extracellular environment. It controls the imports of nutrients to the …
homeostasis of the brain extracellular environment. It controls the imports of nutrients to the …
[HTML][HTML] Blood-brain barrier: more contributor to disruption of central nervous system homeostasis than victim in neurological disorders
M Xiao, ZJ Xiao, B Yang, Z Lan, F Fang - Frontiers in Neuroscience, 2020 - frontiersin.org
The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular
system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by …
system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by …
[HTML][HTML] Damage mechanism and therapy progress of the blood-brain barrier after ischemic stroke
H Gao, H Chen, GY Cui, JX Hu - Cell & Bioscience, 2023 - Springer
The blood-brain barrier (BBB) serves as a defensive line protecting the central nervous
system, while also maintaining micro-environment homeostasis and inhibiting harmful …
system, while also maintaining micro-environment homeostasis and inhibiting harmful …