Abstract The sequence AAUAAA, found 11–30 base pairs (bp) upstream of the poly (A) site
of most non-histone eukaryotic messenger RNAs (mRNAs) 1 forms an essential part of the …

Time after infection (h) Page 1 NATURE NEW BIOLOGY VOL. 233 SEPTEMBER 8 1971 4 %
Table 2 Effect of SV40 and 5-Fluoro 2-deoxyuridine (FUdR) Addition on Autoradiography …

Abstract THE 3′-OH poly (A) segment of globin mRNA ensures the stability of the message
when injected into Xenopus oocytes1–4. We recently developed5 a specific method for the …

Abstract The sequence A–A–U–A–A–A is present in six different purified messenger RNA
molecules (specifically the α-and β-globulin mRNAs of rabbit and human, the …

The specific 3′ termini of a number of eukaryotic mRNAs have been shown to be
generated by the post-transcriptional processing of primary transcripts or pre-mRNAs1–4 …

WE have shown that, when injected into Xenopus oocytes, poly (A) free globin messenger
RNA is translated for a short period of time and then rapidly degraded1–3, while, under the …

The DNA sequences required for the expression of the rabbit β-globin gene in vivo have
been examined. A variety of mutant rabbit β-globin gene templates were linked to a simian …

THE nucleotide sequence of the 5′ non-coding region of messenger RNAs is particularly
interesting because it may contain the signals for processing and modification of mRNA …

We previously demonstrated that a critical 35 bp region 3'of the AAUAAA is required for
rabbit (3-globln mRNA 3'end formation. Recently, we synthesized and tested sequence …

SINCE last reviewed in these columns a little over a year ago 1, several major steps forward
have been made in understanding how the 3'ends of eukaryotic mRNA are formed. First and …