Influence of α-methylation in constructing stapled peptides with olefin metathesis
Q Zhang, X Shi, Y Jiang, Z Li - Tetrahedron, 2014 - Elsevier
Ring-closing metathesis is commonly utilized in peptide macro-cyclization. The influence of
α-methylation of the amino acids bearing the olefin moieties has never been systematically …
α-methylation of the amino acids bearing the olefin moieties has never been systematically …
Metathesis assisted synthesis of cyclic peptides
J Illesinghe, CX Guo, R Garland, A Ahmed… - Chemical …, 2009 - pubs.rsc.org
Metathesis assisted synthesis of cyclic peptides - Chemical Communications (RSC
Publishing) DOI:10.1039/B814092H Royal Society of Chemistry View PDF VersionPrevious …
Publishing) DOI:10.1039/B814092H Royal Society of Chemistry View PDF VersionPrevious …
Highly efficient synthesis of covalently cross‐linked peptide helices by ring‐closing metathesis
HE Blackwell, RH Grubbs - Angewandte Chemie International …, 1998 - Wiley Online Library
Olefin metathesis has been successfully applied to the synthesis of macrocyclic helical
peptides [Eq.(a)]. Carbon–carbon bond tethers between amino acid side chains were …
peptides [Eq.(a)]. Carbon–carbon bond tethers between amino acid side chains were …
A facile conversion of a 310 helical structure to a cyclic β-turn mimic in dehydrophenylalanine-derived small peptides through ring-closing metathesis
T Sastry, B Banerji, SK Kumar, AC Kunwar, J Das… - Tetrahedron letters, 2002 - Elsevier
A facile conversion of a 310 helical structure to a cyclic β-turn mimic in
dehydrophenylalanine-derived small peptides through ring-closing metathesis - ScienceDirect …
dehydrophenylalanine-derived small peptides through ring-closing metathesis - ScienceDirect …
Synthesis of cyclic peptides by ring-closing metathesis
JF Reichwein, C Versluis… - The Journal of organic …, 2000 - ACS Publications
The synthesis of a series of “amide to amide” cyclized peptides by ring-closing metathesis
(RCM) as well as a convenient synthesis for the linear precursors is described. In addition …
(RCM) as well as a convenient synthesis for the linear precursors is described. In addition …
Peptide cyclization via ring-closing metathesis: the N-alkenoxy peptide approach
J Lawrence, M Jourdan, Y Vallée… - Organic & Biomolecular …, 2008 - pubs.rsc.org
The preparation of cyclic hexapeptides from N-hydroxy tripeptides building blocks is
described. Introduction of an unsaturated chain on the hydroxamate oxygen followed by …
described. Introduction of an unsaturated chain on the hydroxamate oxygen followed by …
Structural and pharmacological effects of ring-closing metathesis in peptides
Ø Jacobsen, J Klaveness, P Rongved - Molecules, 2010 - mdpi.com
Molecules | Free Full-Text | Structural and Pharmacological Effects of Ring-Closing Metathesis
in Peptides Next Article in Journal Modulation of Huntingtin Toxicity by BAG1 is Dependent on …
in Peptides Next Article in Journal Modulation of Huntingtin Toxicity by BAG1 is Dependent on …
Modification of constrained peptides by ring-closing metathesis reaction
S Kotha, N Sreenivasachary, K Mohanraja… - Bioorganic & medicinal …, 2001 - Elsevier
Ring-closing metathesis (RCM) with α, α-diallylglycyl peptides is shown to furnish α, α-
cyclopentenylglycyl peptides as conformationally restrained analogues in the form of post …
cyclopentenylglycyl peptides as conformationally restrained analogues in the form of post …
Ring Closing and Macrocyclization of β‐Dipeptides by Olefin Metathesis
B Sundararaju, T Sridhar, M Achard… - European Journal of …, 2013 - Wiley Online Library
Abstract β‐Dipeptides containing allyl groups at different positions on the peptide backbone
were prepared. Ring‐closing metathesis of these β‐dipeptides with the use of a ruthenium …
were prepared. Ring‐closing metathesis of these β‐dipeptides with the use of a ruthenium …
Reversible backbone protection enables combinatorial solid-phase ring-closing metathesis reaction (RCM) in peptides
N Schmiedeberg, H Kessler - Organic letters, 2002 - ACS Publications
Attempts were made to apply the ring-closing metathesis reaction (RCM) to resin-bound
peptides with olefinic side chains of different lengths. In a protein-derived homodetic 10mer …
peptides with olefinic side chains of different lengths. In a protein-derived homodetic 10mer …