Virological failure, HIV-1 drug resistance, and early mortality in adults admitted to hospital in Malawi: an observational cohort study
A Gupta-Wright, K Fielding, JJ van Oosterhout… - The Lancet …, 2020 - thelancet.com
Background Antiretroviral therapy (ART) scale-up in sub-Saharan Africa combined with
weak routine virological monitoring has driven increasing HIV drug resistance. We …
weak routine virological monitoring has driven increasing HIV drug resistance. We …
Risk factors and mortality associated with resistance to first-line antiretroviral therapy: multicentric cross-sectional and longitudinal analyses
L Pinoges, B Schramm, E Poulet, S Balkan… - JAIDS Journal of …, 2015 - journals.lww.com
Background: Understanding the factors associated with HIV drug resistance development
and subsequent mortality is important to improve clinical patient management. Methods …
and subsequent mortality is important to improve clinical patient management. Methods …
HIV-1 virologic failure and acquired drug resistance among first-line antiretroviral experienced adults at a rural HIV clinic in coastal Kenya: a cross-sectional study
AS Hassan, HM Nabwera, SM Mwaringa… - AIDS research and …, 2014 - Springer
Background An increasing number of people on antiretroviral therapy (ART) in sub-Saharan
Africa has led to declines in HIV related morbidity and mortality. However, virologic failure …
Africa has led to declines in HIV related morbidity and mortality. However, virologic failure …
High viral load and multidrug resistance due to late switch to second-line regimens could be a major obstacle to reach the 90-90-90 UNAIDS objectives in sub …
E Guichet, A Aghokeng, L Serrano, G Bado… - AIDS Research and …, 2016 - liebertpub.com
In the context of lifelong antiretroviral treatment (ART) as early as possible and to end the
HIV/AIDS epidemic as a public health treat by 2030, it is important to evaluate the potential …
HIV/AIDS epidemic as a public health treat by 2030, it is important to evaluate the potential …
Virological outcome and patterns of HIV‐1 drug resistance in patients with 36 months' antiretroviral therapy experience in Cameroon
AF Aghokeng, C Kouanfack… - Journal of the …, 2013 - Wiley Online Library
Introduction The current expansion of antiretroviral treatment (ART) in the developing world
without routine virological monitoring still raises concerns on the outcome of the strategy in …
without routine virological monitoring still raises concerns on the outcome of the strategy in …
Determinants of virological failure and antiretroviral drug resistance in Mozambique
M Rupérez, C Pou, S Maculuve… - Journal of …, 2015 - academic.oup.com
Objectives The objective of this study was to inform public health actions to limit first-line
ART failure and HIV drug resistance in Mozambique. Methods This was a cross-sectional …
ART failure and HIV drug resistance in Mozambique. Methods This was a cross-sectional …
Virological failure rates and HIV‐1 drug resistance patterns in patients on first‐line antiretroviral treatment in semirural and rural Gabon
F Liégeois, C Vella, S Eymard‐Duvernay… - Journal of the …, 2012 - Wiley Online Library
Introduction As antiretroviral treatment (ART) continues to expand in resource‐limited
countries, the emergence of HIV drug resistance mutations (DRMs) is challenging in these …
countries, the emergence of HIV drug resistance mutations (DRMs) is challenging in these …
Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa
Abstract Background KwaZulu-Natal (KZN) Province in South Africa has the highest HIV
disease burden in the country, with an estimated population prevalence of 24.7%. A pilot …
disease burden in the country, with an estimated population prevalence of 24.7%. A pilot …
Effect of pretreatment HIV-1 drug resistance on immunological, virological, and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a …
RL Hamers, R Schuurman, KCE Sigaloff… - The Lancet infectious …, 2012 - thelancet.com
Background The effect of pretreatment HIV-1 drug resistance on the response to first-line
combination antiretroviral therapy (ART) in sub-Saharan Africa has not been assessed. We …
combination antiretroviral therapy (ART) in sub-Saharan Africa has not been assessed. We …
Nationwide estimates of viral load suppression and acquired HIV drug resistance in Cameroon
GF Tchouwa, S Eymard-Duvernay, A Cournil… - …, 2018 - thelancet.com
Background Population-based studies to estimate viral load (VL) suppression and rate of
acquired HIV drug resistance (ADR) are essential in sub-Saharan Africa. We conducted the …
acquired HIV drug resistance (ADR) are essential in sub-Saharan Africa. We conducted the …