Diagnosis of antiretroviral therapy failure in Malawi: poor performance of clinical and immunological WHO criteria
JJG Van Oosterhout, L Brown, R Weigel… - Tropical medicine & …, 2009 - Wiley Online Library
Objectives In antiretroviral therapy (ART) scale‐up programmes in sub‐Saharan Africa viral
load monitoring is not recommended. We wanted to study the impact of only using clinical …
load monitoring is not recommended. We wanted to study the impact of only using clinical …
Short-term risk of AIDS or death in people infected with HIV-1 before antiretroviral therapy in South Africa: a longitudinal study
Summary Background In sub-Saharan Africa, data for short-term risk of AIDS or death, which
might inform decisions about when to start antiretroviral therapy (ART), are scarce. Our aim …
might inform decisions about when to start antiretroviral therapy (ART), are scarce. Our aim …
Trends in pretreatment HIV-1 drug resistance in antiretroviral therapy-naive adults in South Africa, 2000–2016: a pooled sequence analysis
B Chimukangara, RJ Lessells, SY Rhee… - …, 2019 - thelancet.com
Abstract Background South Africa has the largest public antiretroviral therapy (ART)
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …
Identifying gaps in HIV service delivery across the diagnosis‐to‐treatment cascade: findings from health facility surveys in six sub‐Saharan countries
Introduction: Despite the rollout of antiretroviral therapy (ART), challenges remain in
ensuring timely access to care and treatment for people living with HIV. As part of a multi …
ensuring timely access to care and treatment for people living with HIV. As part of a multi …
Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto, South Africa
Z El-Khatib, AM Ekstrom, J Ledwaba, L Mohapi… - Aids, 2010 - journals.lww.com
Background: We assessed risk factors for viremia and drug resistance among long-term
recipients of antiretroviral therapy (ART) in South Africa. Methods: In 2008, we conducted a …
recipients of antiretroviral therapy (ART) in South Africa. Methods: In 2008, we conducted a …
Mortality and loss-to-follow-up during the pre-treatment period in an antiretroviral therapy programme under normal health service conditions in Uganda
B Amuron, G Namara, J Birungi, C Nabiryo, J Levin… - BMC public health, 2009 - Springer
Background In many HIV programmes in Africa, patients are assessed clinically and
prepared for antiretroviral treatment over a period of 4–12 weeks. Mortality rates following …
prepared for antiretroviral treatment over a period of 4–12 weeks. Mortality rates following …
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa
J Manasa, RJ Lessells, A Skingsley, KK Naidu… - PloS one, 2013 - journals.plos.org
Objective To determine the frequency and patterns of acquired antiretroviral drug resistance
in a rural primary health care programme in South Africa. Design Cross-sectional study …
in a rural primary health care programme in South Africa. Design Cross-sectional study …
Resistance testing for management of HIV virologic failure in sub-Saharan Africa: an unblinded randomized controlled trial
MJ Siedner, MYS Moosa, S McCluskey… - Annals of internal …, 2021 - acpjournals.org
Background: Virologic failure in HIV predicts the development of drug resistance and
mortality. Genotypic resistance testing (GRT), which is the standard of care after virologic …
mortality. Genotypic resistance testing (GRT), which is the standard of care after virologic …
Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia
A Abdissa, D Yilma, J Fonager, AM Audelin… - BMC infectious …, 2014 - Springer
Background The ongoing scale-up of antiretroviral therapy (ART) in sub-Saharan Africa has
prompted the interest in surveillance of transmitted and acquired HIV drug resistance …
prompted the interest in surveillance of transmitted and acquired HIV drug resistance …
HIV-1 drug resistance and third-line therapy outcomes in patients failing second-line therapy in Zimbabwe
C Chimbetete, D Katzenstein, T Shamu… - Open forum …, 2018 - academic.oup.com
Objectives To analyze the patterns and risk factors of HIV drug resistance mutations among
patients failing second-line treatment and to describe early treatment responses to …
patients failing second-line treatment and to describe early treatment responses to …