Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa
TS Boender, CM Kityo, RS Boerma… - Journal of …, 2016 - academic.oup.com
Objectives Limited availability of viral load (VL) monitoring in HIV treatment programmes in
sub-Saharan Africa can delay switching to second-line ART, leading to the accumulation of …
sub-Saharan Africa can delay switching to second-line ART, leading to the accumulation of …
Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virological failure in Rwanda
JA Ndahimana, DJ Riedel… - Tropical Medicine & …, 2016 - Wiley Online Library
Objective To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in
a large cohort of patients receiving first‐line tenofovir‐based antiretroviral therapy (ART) …
a large cohort of patients receiving first‐line tenofovir‐based antiretroviral therapy (ART) …
Prevalence of pre-antiretroviral-treatment drug resistance by gender, age, and other factors in HIV-infected individuals initiating therapy in Kenya, 2013–2014
RA Silverman, IA Beck, C Kiptinness… - The Journal of …, 2017 - academic.oup.com
Background Pre-antiretroviral-treatment drug resistance (PDR) is a predictor of human
immunodeficiency virus (HIV) treatment failure. We determined PDR prevalence and …
immunodeficiency virus (HIV) treatment failure. We determined PDR prevalence and …
[HTML][HTML] HIV drug resistance in sub-Saharan Africa: public health questions and the potential role of real-world data and mathematical modelling
The prevalence of pretreatment resistance to non-nucleoside reverse transcriptase inhibitors
(NNRTIs) is> 10% in many low-income countries. As a consequence, several sub-Saharan …
(NNRTIs) is> 10% in many low-income countries. As a consequence, several sub-Saharan …
The continuing burden of advanced HIV disease over 10 years of increasing antiretroviral therapy coverage in South Africa
M Osler, K Hilderbrand, E Goemaere… - Clinical Infectious …, 2018 - academic.oup.com
Background Antiretroviral treatment (ART) has been massively scaled up to decrease
human immunodeficiency virus (HIV)–related morbidity, mortality, and HIV transmission …
human immunodeficiency virus (HIV)–related morbidity, mortality, and HIV transmission …
Disease patterns and causes of death of hospitalized HIV‐positive adults in West Africa: a multicountry survey in the antiretroviral treatment era
C Lewden, YJ Drabo, DM Zannou… - Journal of the …, 2014 - Wiley Online Library
Objective We aimed to describe the morbidity and mortality patterns in HIV‐positive adults
hospitalized in West Africa. Method We conducted a six‐month prospective multicentre …
hospitalized in West Africa. Method We conducted a six‐month prospective multicentre …
Low primary and secondary HIV drug-resistance after 12 months of antiretroviral therapy in human immune-deficiency virus type 1 (HIV-1)-infected individuals from …
J Rusine, B Asiimwe-Kateera, J van de Wijgert… - PloS one, 2013 - journals.plos.org
Treatment outcomes of HIV patients receiving antiretroviral therapy (ART) in Rwanda are
scarcely documented. HIV viral load (VL) and HIV drug-resistance (HIVDR) outcomes at …
scarcely documented. HIV viral load (VL) and HIV drug-resistance (HIVDR) outcomes at …
High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa
EM Etta, L Mavhandu, C Manhaeve… - AIDS research and …, 2017 - Springer
Background Combination antiretroviral therapy (cART) has significantly reduced HIV
morbidity and mortality in both developed and developing countries. However, the …
morbidity and mortality in both developed and developing countries. However, the …
Determinants of mortality and loss to follow-up among adults enrolled in HIV care services in Rwanda
V Mugisha, CA Teasdale, C Wang, M Lahuerta… - PLOS …, 2014 - journals.plos.org
Background Antiretroviral therapy (ART) improves morbidity and mortality in patients with
HIV, however high rates of loss to follow-up (LTF) and mortality have been documented in …
HIV, however high rates of loss to follow-up (LTF) and mortality have been documented in …
Baseline predictors of antiretroviral treatment failure and lost to follow up in a multicenter countrywide HIV-1 cohort study in Ethiopia
NF Telele, AW Kalu, G Marrone, S Gebre-Selassie… - PloS one, 2018 - journals.plos.org
Background Antiretroviral therapy (ART) has been rapidly scaled up in Ethiopia since 2005,
but factors influencing the outcome are poorly studied. We therefore analysed baseline …
but factors influencing the outcome are poorly studied. We therefore analysed baseline …