Apicomplexan parasites infectious to humans include Plasmodium spp., Babesia spp.,
Toxoplasma gondii, Cryptosporidium spp., Isospora belli and Cyclospora cayetanensis. With …

The human malaria parasite Plasmodium falciparum harbors a relict, nonphotosynthetic
plastid of algal origin termed the apicoplast. Although considerable progress has been …

Toxoplasma gondii is a widespread intracellular pathogen infecting humans and a variety of
animals. Previous studies have shown that Toxoplasma uses glucose and glutamine as the …

Malaria parasites contain an essential organelle called the apicoplast that houses metabolic
pathways for fatty acid, heme, isoprenoid, and iron–sulfur cluster synthesis. Surprisingly …

Apicomplexa are some of the most widespread and poorly controlled pathogens in the
world. The metabolism of lipids in these parasites, which include Plasmodium spp …

The fatty acid synthesis type II pathway has received considerable interest as a candidate
therapeutic target in Plasmodium falciparum asexual blood-stage infections. This apicoplast …

Apicomplexa are important pathogens that include the causative agents of malaria,
toxoplasmosis, and cryptosporidiosis. Apicomplexan parasites contain a relict chloroplast …

Malaria parasites scavenge nutrients from their host but also harbour enzymatic pathways
for de novo macromolecule synthesis. One such pathway is apicoplast‐targeted type II fatty …

Toxoplasma gondii is an obligate intracellular parasite from the phylum Apicomplexa. A
hallmark of these protozoans is the presence of a unique apical complex of organelles that …

Many apicomplexan parasites, such as Toxoplasma gondii and Plasmodium species,
possess a nonphotosynthetic plastid, referred to as the apicoplast, which is essential for the …