Rationale and Objectives: Up to 20% of idiopathic interstitial lung disease is familial, referred
to as familial pulmonary fibrosis (FPF). An integrated analysis of FPF genetic risk was …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare, irreversible, and progressive disease
of the lungs. Common genetic variants, in addition to nongenetic factors, have been …

Idiopathic pulmonary fibrosis (IPF) is a genetic heterogeneous disease with high mortality
and poor prognosis. However, a large fraction of genetic cause remains unexplained …

Rationale: Idiopathic pulmonary fibrosis (IPF) is an increasingly recognized, often fatal lung
disease of unknown etiology. Objectives: The aim of this study was to use whole-exome …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …

Pulmonary fibrosis comprises a wide range of fibrotic lung diseases with unknown
pathogenesis and poor prognosis. Familial pulmonary fibrosis (FPF) represents a unique …

Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis.
Genome-wide association studies have identified common variants, or those with a minor …

Background Several genetic variants are associated with the risk of idiopathic pulmonary
fibrosis (IPF). These have not been systematically reviewed. Methods We searched the …

Idiopathic pulmonary fibrosis (IPF) is a severe lung disease characterized by progressive
interstitial fibrosis. The etiology of IPF is complex and includes a substantial genetic …

Genetic predisposition to pulmonary fibrosis has been confirmed by the discovery of several
gene mutations that cause pulmonary fibrosis. Although genetic sequencing of familial …