Detection of a novel CBFB-MYH11 fusion transcript in acute myeloid leukemia M1 with inv (16)(p13q22)

K Kurata, K Yamamoto, Y Okazaki, Y Noguchi, K Matsui… - Cancer Genetics, 2020 - Elsevier
Acute myeloid leukemia (AML) with an inv (16)(p13q22) or t (16; 16)(p13; q22) chromosomal
abnormality represents one of the most common subtypes of de novo cases. These …

[HTML][HTML] Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

S Opatz, S Vosberg, B Ksienzyk, S Tschuri, A Graf… - Blood, 2018 - Elsevier
The leukemia-associated fusion gene CBFB/MYH11 results from a pericentric inversion of
chromosome 16, inv (16)(p13. 1q22), or less commonly from at (16; 16)(p13. 1; q22) …

CBFB/MYH11 fusion in a patient with AML‐M4Eo and cytogenetically normal chromosomes 16

H Pirc‐Danoewinata, HG Dauwerse… - Genes …, 2000 - Wiley Online Library
We present a unique case of acute myeloid leukemia M4Eo (AML‐M4Eo) with a
CBFB/MYH11 fusion transcript and a trisomy 22, but in whom cytogenetic analyses did not …

Acute myeloid leukemia with t (16; 16)(p13; q22) showing a new CBFB-MYH11 fusion transcript associated with an atypical leukemic blasts morphology

F Albano, L Anelli, A Zagaria, N Coccaro, G Tota… - Human pathology, 2014 - Elsevier
Acute myeloid leukemia (AML) cases with inv (16)(p13q22) or t (16; 16)(p13; q22) are
characterized by multiple CBFB-MYH11 fusion transcripts, type A being the most frequent …

A unique structural abnormality of chromosome 16 resulting in a CBFβ-MYH11 fusion transcript in a patient with acute myeloid leukemia, FAB M4

J O'Reilly, L Chipper, F Springall… - Cancer genetics and …, 2000 - Elsevier
A 43-year-old female with a peripheral white cell count of 118.0× 109/L and 96% blasts was
diagnosed with acute myeloid leukemia (AML), FAB M4. Cytogenetics, performed on a bone …

Banding and molecular cytogenetic studies detected a CBFB-MYH11 fusion gene that appeared as abnormal chromosomes 1 and 16 in a baby with acute myeloid …

MLM Silva, SC Raimondi, E Abdelhay, M Gross… - Cancer genetics and …, 2008 - Elsevier
The acute myeloid leukemia (AML) subtype M4Eo occurs in 5% of all AML cases and is
usually associated with either an inv (16)(p13. 1q22) or at (16; 16)(p13. 1; q22) …

De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature

VR Sethapati, R Jabr, L Shune… - Case Reports in …, 2020 - Wiley Online Library
Acute myeloid leukemia (AML) with inv (16)(p13. 1q22) resulting in CBFB-MYH11 fusion is
associated with a favorable prognosis. The presence of a KIT mutation modifies it to an …

[HTML][HTML] A novel cryptic CBFB-MYH11 gene fusion present at birth leading to acute myeloid leukemia and allowing molecular monitoring for minimal residual disease

PJ Poddighe, MA Veening, MB Mansur… - Human Pathology: Case …, 2018 - Elsevier
Acute myeloid leukemia (AML) with the inv (16)/t (16; 16) karyotype is associated with a
favourable prognosis, showing longer periods of complete remission and high overall …

[HTML][HTML] Acute myeloid leukemia with cryptic CBFB-MYH11 type D

T Kobayashi, M Ichikawa, Y Kamikubo… - International Journal of …, 2013 - ncbi.nlm.nih.gov
A 77 year-old female was found with FAB M4Eo acute myeloid leukemia. Although CBFB-
MYH11 mRNA was detected in RT-PCR, the conventional cytogenetic analysis failed to …

Detection of the CBFB/MYH11 fusion gene in de novo acute myeloid leukemia (AML): a single-institution study of 224 Japanese AML patients

F Monma, K Nishii, J Shiga, H Sugahara, Y Watanabe… - Leukemia research, 2007 - Elsevier
The cytogenetic findings in acute myeloid leukemia (AML) are a powerful prognostic
indicator. Among these abnormalities, the World Health Organization has classified inv …