Infantile spasms syndrome, West syndrome and related phenotypes: what we know in 2013

P Pavone, P Striano, R Falsaperla, L Pavone… - Brain and …, 2014 - Elsevier
The current spectrum of disorders associated to clinical spasms with onset in infancy is
wider than previously thought; accordingly, its terminology has changed. Nowadays, the …

Symptomatology of infantile spasms

K Watanabe, T Negoro, A Okumura - Brain and Development, 2001 - Elsevier
Epileptic spasms in West syndrome consist of a brief phasic contraction followed by a
gradually relaxing tonic component, associated with typical ictal electroencephalographic …

A proposal for case definitions and outcome measures in studies of infantile spasms and West syndrome: consensus statement of the West Delphi group

AL Lux, JP Osborne - Epilepsia, 2004 - Wiley Online Library
Purpose: To reach a broad consensus on case definitions, outcomes, and outcome
measures that will ease future study design and facilitate comparison of data from different …

[HTML][HTML] West syndrome: a comprehensive review

P Pavone, A Polizzi, SD Marino, G Corsello… - Neurological …, 2020 - Springer
Since its first clinical description (on his son) by William James West (1793–1848) in 1841,
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …

Efficacy of treatments for infantile spasms: a systematic review

JM Song, J Hahn, SH Kim… - Clinical …, 2017 - journals.lww.com
Objectives West syndrome (also known as infantile spasm because of its main seizure type)
is a rare form of epilepsy that begins during early infancy. Recent guidelines and reviews on …

The underlying etiology of infantile spasms (West syndrome): Information from the United Kingdom Infantile Spasms Study (UKISS) on contemporary causes and their …

JP Osborne, AL Lux, SW Edwards, E Hancock… - …, 2010 - Wiley Online Library
Purpose: To examine the underlying etiology of infantile spasms from the United Kingdom
Infantile Spasms Study (UKISS), using the pediatric adaptation of ICD 10. Methods: Infants …

Neurophysiology of spasms

F Vigevano, L Fusco, C Pachatz - Brain and Development, 2001 - Elsevier
Spasms are a form of epileptic seizure typical of infancy. From a clinical point of view, the
child presents a flexor–extensor movement involving the trunk and limbs and lasting about …

Infantile epileptic encephalopathy with hypsarrhythmia (infantile spasms/West syndrome)

RA Hrachovy, JD Frost Jr - Journal of clinical neurophysiology, 2003 - journals.lww.com
Infantile spasms is a unique disorder peculiar to infancy and early childhood. In this article,
the clinical manifestations and electroencephalographic features of the disorder are …

West syndrome: a review and guide for paediatricians

R D'Alonzo, D Rigante, E Mencaroni… - Clinical drug …, 2018 - Springer
West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak
between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on …

Infantile spasms

EH Kossoff - The neurologist, 2010 - journals.lww.com
Background: Infantile spasms (West syndrome) is an epilepsy condition affecting 1 in 2000
infants. Perhaps no more worrisome neurologic disorder exists because of its frequent …