There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain
and various psychiatric disorders, however, there is scant evidence that oxytocin reaches …

The neuropeptide oxytocin plays an evolutionarily conserved role in mammalian social
behavior. Despite striking effects on animal social behavior after intracerebroventricular drug …

Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …

Following the discovery that intranasal administration of neuropeptides can reach the central
nervous system, a growing number of studies applied intranasal oxytocin (OT) paradigms to …

Background Approximately 1.7 million Americans sustain a traumatic brain injury (TBI) each
year and chronic pain is a common complication. Objective We studied the effects of …

Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …

Intranasal oxytocin is attracting attention as a potential treatment for several brain disorders
due to promising preclinical results. However, translating findings to humans has been …

Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Intranasal delivery of oxytocin (Oxt) has been identified as a potential therapeutic to target
human conditions characterized by social deficits, yet the ability of this administrative route …

Oxytocin (OT) is a neuropeptide that mediates a variety of complex social behaviors in
animals and humans. Intranasal OT has been used as an experimental therapeutic for …