Aerosol delivery from a metered-dose inhaler during mechanical ventilation. An in vitro model.

JB Fink, R Dhand, AG Duarte, JW Jenne… - American journal of …, 1996 - atsjournals.org
Successful bronchodilator therapy with a metered-dose inhaler (MDI) in intubated,
mechanically ventilated patients requires adequate delivery of aerosol to the lower …

Albuterol delivery in a model of mechanical ventilation. Comparison of metered-dose inhaler and nebulizer efficiency.

P Diot, L Morra, GC Smaldone - American journal of respiratory and …, 1995 - atsjournals.org
Using an in vitro model, we compared efficiencies of jet nebulizers and metered-dose
inhalers (MDI) with actuator devices to deliver albuterol in various conditions of mechanical …

[HTML][HTML] In vitro evaluation of aerosol bronchodilator delivery during mechanical ventilation: pressure-control vs. volume control ventilation

DR Hess, C Dillman, RM Kacmarek - Intensive care medicine, 2003 - Springer
Objective To determine the effect of inspiratory time and inspiratory flow pattern on albuterol
delivery by aerosol during mechanical ventilation. Design A ventilator was connected to a …

[HTML][HTML] Maximizing aerosol delivery during mechanical ventilation: go with the flow and go slow

R Dhand - Intensive care medicine, 2003 - Springer
During the past decade the unprecedented improvements in technology for delivery of
inhaled drugs were matched by an equally impressive growth in clinical applications …

Aerosol delivery during mechanical ventilation: a predictive in-vitro lung model

HD Fuller, MB Dolovich, C Chambers… - Journal of aerosol …, 1992 - liebertpub.com
Objective: to compare aerosol delivery from a standard (Bennett) nebulizer, a submicronic
(Ultravent) nebulizer, a metered dose inhaler (MDI) plus small holding chamber, and an MDI …

Bronchodilator delivery by metered-dose inhaler in ventilator-supported patients.

R Dhand, A Jubran, MJ Tobin - American journal of respiratory and …, 1995 - atsjournals.org
The optimal dose and technique for administration of bronchodilators with a metered-dose
inhaler (MDI) in mechanically ventilated patients have not been established. We studied the …

Basic techniques for aerosol delivery during mechanical ventilation

R Dhand - Respiratory Care, 2004 - rc.rcjournal.com
Among the devices employed for aerosol generation (metered-dose inhalers, nebulizers,
and dry powder inhalers) only metered-dose inhalers and nebulizers are routinely employed …

Aerosol therapy in mechanically ventilated patients: recent advances and new techniques

JB Fink, R Dhand - Seminars in respiratory and critical care …, 2000 - thieme-connect.com
Therapeutic aerosols are commonly used in mechanically ventilated patients, yet
information regarding their efficacy and optimal technique of administration has been …

Aerosol delivery during mechanical ventilation: from basic techniques to new devices

R Dhand - Journal of aerosol medicine and pulmonary drug …, 2008 - liebertpub.com
Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for
aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol …

Dose-response to bronchodilator delivered by metered-dose inhaler in ventilator-supported patients.

R Dhand, AG Duarte, A Jubran, JW Jenne… - American journal of …, 1996 - atsjournals.org
In nonintubated patients, metered-dose inhalers (MDIs) are accepted as the most
convenient, efficient, and cost effective method of administering inhaled bronchodilators …