Clostridium difficile is an anaerobic, gram positive, sporulating, toxin-producing bacillus
which causes a spectrum of clinical disease ranging from an asymptomatic carrier state to …

There have been a number of advances in probiotics and our understanding of their role in
prevention of CDI, but a number of important safety and efficacy questions remain. An …

Due to morbidity, mortality, and high costs associated with eradicating Clostridium difficile
once this organism causes colitis, this bacterium has been termed one of the most …

Despite advances in the diagnosis and treatment of Clostridium difficile infection (CDI) and
prevention efforts to reduce the spread of C. difficile, CDI remains a significant challenge to …

Background Clostridium difficile is a pathogen of rapidly increasing public health
importance. An estimated quarter of a million Clostridium difficile infections (CDI) occur in …

In the past two years an enormous amount of molecular, genetic, metabolomic and
mechanistic data on the host-bacterium interaction, a healthy gut microbiota and a possible …

Antimicrobials are effective agents used to combat virulent bacterial, yeast, and fungal
infections that may otherwise cause rampant disease leading to skyrocketing …

Clostridium difficile diarrhea is an expensive, life-threatening infection associated with
serious morbidity and mortality, even among previously healthy individuals. Relapses from …

With the end of the golden era of antibiotic discovery, the emergence of a new post-antibiotic
age threatens to thrust global health and modern medicine back to the pre-antibiotic era …

Clostridium difficile infection (CDI) is one of the most prevalent nosocomial infections. A
dramatic increase in the incidence and severity of CDI has been noted in the past decade …