C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks–final results of the IMPACT 2 study

TJ Craig, AK Bewtra, SL Bahna, D Hurewitz… - Allergy, 2011 - Wiley Online Library
To cite this article: Craig TJ, Bewtra AK, Bahna SL, Hurewitz D, Schneider LC, Levy RJ, Moy
JN, Offenberger J, Jacobson KW, Yang WH, Eidelman F, Janss G, Packer FR, Rojavin MA …

Effect of time to treatment on response to C1 esterase inhibitor concentrate for hereditary angioedema attacks

TJ Craig, MA Rojavin, T Machnig, HO Keinecke… - Annals of allergy …, 2013 - Elsevier
Background C1 esterase inhibitor (C1-INH) concentrate is well established as effective
therapy for hereditary angioedema (HAE). It is thought that treatment of an acute HAE attack …

Update on the use of C1-esterase inhibitor replacement therapy in the acute and prophylactic treatment of hereditary angioedema

H Henry Li, M Riedl, J Kashkin - Clinical reviews in allergy & immunology, 2019 - Springer
In the vast majority of patients with hereditary angioedema (HAE), angioedema attacks are
due to the quantitative or functional deficiency of C1-esterase inhibitor (C1-INH), which …

[HTML][HTML] Recombinant human-C1 inhibitor is effective and safe for repeat hereditary angioedema attacks

HH Li, D Moldovan, JA Bernstein, A Reshef… - The Journal of Allergy …, 2015 - Elsevier
Background Hereditary angioedema (HAE) caused by a deficiency in functional C1 esterase
inhibitor (C1INH) is characterized by recurrent episodes of cutaneous and/or …

Treatment with C1-esterase inhibitor concentrate in type I or II hereditary angioedema: a systematic literature review.

K Bork, I Steffensen, T Machnig - Allergy & Asthma …, 2013 - search.ebscohost.com
Hereditary angioedema (HAE) due to C1 esterase inhibitor (HAE-CI-INH) deficiency is a rare
genetic disorder presenting with recurrent episodes of skin swellings, abdominal pain …

Population pharmacokinetics of plasma-derived C1 esterase inhibitor concentrate used to treat acute hereditary angioedema attacks

JA Bernstein, B Ritchie, RJ Levy, RL Wasserman… - Annals of Allergy …, 2010 - Elsevier
BACKGROUND: C1 esterase inhibitor (C1-INH) replacement is recommended as a first-line
therapy for acute edema attacks in hereditary angioedema (HAE). Only limited …

Recombinant human C1 inhibitor for the prophylaxis of hereditary angioedema attacks: a pilot study

A Reshef, D Moldovan, K Obtulowicz, I Leibovich… - Allergy, 2013 - Wiley Online Library
Background Hereditary angioedema (HAE) is a disease characterized by recurrent tissue
swelling affecting various body locations. Recent literature shows that patients with frequent …

Recombinant human C1-esterase inhibitor relieves symptoms of hereditary angioedema attacks: phase 3, randomized, placebo-controlled trial

MA Riedl, JA Bernstein, H Li, A Reshef, W Lumry… - Annals of Allergy …, 2014 - Elsevier
Background Hereditary angioedema (HAE), caused by C1 inhibitor (C1INH) deficiency or
dysfunction, is characterized by recurrent attacks of tissue swelling affecting multiple …

[HTML][HTML] Clinical profile and treatment outcomes in patients with hereditary angioedema with normal C1 esterase inhibitor

DH Jones, P Bansal, JA Bernstein, S Fatteh… - World Allergy …, 2022 - Elsevier
Background Hereditary angioedema (HAE) is often caused by low serum levels or functional
deficiency in C1 inhibitor (C1-INH); however, in some cases, C1-INH serum level and …

Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study

MA Riedl, RJ Levy, D Suez, RF Lockey… - Annals of Allergy …, 2013 - Elsevier
BACKGROUND: The efficacy of recombinant human C1 inhibitor (rhC1INH) for the treatment
of patients with acute hereditary angioedema (HAE) attacks has been demonstrated in 2 …