Idiopathic pulmonary fibrosis: new and emerging treatment options

RJ Hewitt, TM Maher - Drugs & Aging, 2019 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive and debilitating, scarring lung disease
with a worse prognosis than some cancers. The incidence of IPF is increasing and while …

Idiopathic pulmonary fibrosis: recent advances on pharmacological therapy

P Spagnolo, TM Maher, L Richeldi - Pharmacology & therapeutics, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal of the idiopathic interstitial
pneumonias with an estimated 5-year survival of approximately 20%. In the last two decades …

[HTML][HTML] Advances in the management of idiopathic pulmonary fibrosis

JH Ryu, CE Daniels - F1000 medicine reports, 2010 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a common form of interstitial lung disease and usually
results in progressive respiratory insufficiency and death. Steady progress has been made …

Idiopathic pulmonary fibrosis: an update

P Spagnolo, N Sverzellati, G Rossi, A Cavazza… - Annals of …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic
interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults …

[HTML][HTML] Idiopathic pulmonary fibrosis: diagnostic pitfalls and therapeutic challenges

P Spagnolo, R Tonelli, E Cocconcelli, A Stefani… - Multidisciplinary …, 2012 - Springer
Idiopathic pulmonary fibrosis (IPF), the most common of the idiopathic interstitial
pneumonias, is a devastating condition that carries a prognosis worse than that of many …

The big clinical trials in idiopathic pulmonary fibrosis

F Luppi, P Spagnolo, S Cerri… - Current opinion in …, 2012 - journals.lww.com
Despite multiple clinical trials, there is no strong, definitive evidence in favor of any agent to
treat IPF. On the other hand, the placebo arms of these large trials have provided us with …

[HTML][HTML] Idiopathic pulmonary fibrosis: an update on pathogenesis

Q Mei, Z Liu, H Zuo, Z Yang, J Qu - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

Pharmacological treatment of idiopathic pulmonary fibrosis: current approaches, unsolved issues, and future perspectives

M Kreuter, F Bonella, M Wijsenbeek… - BioMed research …, 2015 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a devastating condition with a 5‐year survival of
approximately 20%. The disease primarily occurs in elderly patients. IPF is a highly …

Advances in the treatment of idiopathic pulmonary fibrosis

A Sergew, KK Brown - Expert Opinion on Emerging Drugs, 2015 - Taylor & Francis
Introduction: Idiopathic pulmonary fibrosis (IPF) is a lung limited, progressive fibrotic disease
with a poor prognosis. The cause is unknown, and currently there is no treatment that …

A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials

HR Collard, WZ Bradford, V Cottin… - European …, 2015 - Eur Respiratory Soc
The past decade has seen substantial progress in understanding the pathobiology, natural
history, and clinical significance of idiopathic pulmonary fibrosis (IPF), culminating in the …