Activation of adenosine A2A receptors (A2AR) has been shown to antagonize the function of
D2 dopaminergic regulation of striatal γ‐aminobutyric acid (GABA)‐ergic output and, thus …

The effects on locomotor activity (LA) of selective agonists for adenosine receptor subtypes
were examined in mice following bilateral injections into the nucleus accumbens (ACB). The …

The stable analogues of adenosine, N-ethylcarboxamidoadenosine (NECA), R-
phenylisopropyladenosine (R-PIA) and cyclohexyladenosine (CHA), dose-dependently …

The cellular distribution of adenosine A2A receptor messenger RNA in the central nervous
system was investigated using in situ hybridization with ribonucleotide probes. A specific …

The effects on striatal dopamine (DA) release and metabolism by local administration of
adenosine analogues with different affinities for the A 1 and A 2 adenosine receptors, were …

Caffeine, the most widely consumed of all psychostimulant drugs, exerts its action by
antagonizing adenosine receptors. To study the arousing properties of caffeine, we injected …

Adenosine A2A receptor antagonists have been proposed as an effective therapy in the
treatment of Parkinson's disease. To explore the possibility that dopamine denervation may …

The antagonistic interactions between adenosine A 1 and dopamine D 1 receptors were
studied in a mouse Ltk− cell line stably cotransfected with human adenosine A 1 receptor …

Adenosine modulates dopamine in the brain via A1 and A2A receptors, but that modulation
has only been characterized on a slow time scale. Recent studies have characterized a …

It is well known that the nucleoside adenosine exerts a modulatory influence in the central
nervous system by activating G protein coupled receptors. Adenosine A2A receptors, the …