Evaluation of adenosine A2 receptor function in the mammalian CNS has been impeded by
the lack ofhighly selective A2 receptor agonists. The present investigations describe the …

There has been a long debate about the predominant involvement of the different adenosine
receptor subtypes and the preferential role of pre‐versus post‐synaptic mechanisms in the …

The present experiments tested the hypothesis that adenosine A2 receptors are involved in
central reward function. Adenosine receptor agonists or antagonists were administered to …

In this study, we have used the selective A2A adenosine receptor antagonist KW6002 to
investigate the function of A2A receptors in the Lister hooded rat nucleus accumbens in vitro …

The ventral tegmental area (VTA) plays an important role in reward and motivational
processes that facilitate the development of drug addiction. Glutamatergic inputs into the …

Recent studies have shown the existence of a specific antagonistic interaction between
adenosine A 2a receptors and dopamine D 2 receptors in the brain. This A 2a-D 2 …

Caffeine, the most widely used psychoactive compound, is an adenosine receptor
antagonist. It promotes wakefulness by blocking adenosine A2A receptors (A2ARs) in the …

Although molecular biology studies indicate the presence of adenosine A2A receptors in the
rat hippocampus, the pharmacological characterization of adenosine A2A receptor binding …

We have previously found, in striatal membrane preparations from young (2 months old)
rats, that stimulation of adenosine A 2 receptors (with the selective adenosine A 2 agonist …

Adenosine A2 receptors were labeled and visualized by autoradiography in tissue sections
of the human brain using the A2-selective agonist ligand [3 H](2-p-(2-car☐ yethyl) …