Specific identification of fibrin polymers, fibrinogen degradation products, and crosslinked fibrin degradation products in plasma and serum with a new sensitive …

DG Connaghan, CW Francis, DA Lane, VJ Marder - 1985 - ashpublications.org
A new method is described for identifying low concentrations of circulating derivatives of
fibrinogen and fibrin, even when present in heterogeneous mixtures. This technique is …

Functional test and reagent for determining fibrinogen

K Fickenscher - US Patent 5,292,664, 1994 - Google Patents
A method and reagent for determining fibrinogen from undiluted plasma samples. The use of
undiluted plasma as sample is made possible by the use of a specific peptide inhibitor of …

Measurement of cross linked fibrin derivatives in plasma: an immunoassay using monoclonal antibodies.

AN Whitaker, MJ Elms, PP Masci… - Journal of clinical …, 1984 - jcp.bmj.com
Fibrinogen degradation, fibrin polymerisation, and the insertion of cross links into fibrin by
fibrin stabilising factor lead to the appearance of new antigenic determinants. Antibodies …

Assay for soluble crosslinked fibrin polymers

VJ Marder, CW Francis - US Patent 5,206,140, 1993 - Google Patents
This invention relates to an assay for fibrin polymers for use in the diagnosis of patients at
risk of thrombosis and in monitoring the effects of treatment in such patients. More …

The use of soluble fibrin in evaluating the acute and chronic hypercoagulable state

CE Dempfle - Thrombosis and haemostasis, 1999 - thieme-connect.com
Systemic coagulation activation can be triggered by a variety of mechanisms, leading to the
disseminated intravascular coagulation syndrome. 28, 29 Since coagulation activation takes …

Detection of circulating crosslinked fibrin derivatives by a heat extraction-SDS gradient gel electrophoretic technique

CW Francis, VJ Marder, SE Martin - 1979 - ashpublications.org
A technique has been developed to identify and quantitate unique plasmic degradation
products of crosslinked fibrin in plasma. In this method, fibrin derivatives are extracted by …

Anti-human soluble fibrin antibody, hybridoma, and immunoassaying method

G Soe, I Kohno, K Inuzuka, Y Ito - US Patent 5,821,068, 1998 - Google Patents
57 ABSTRACT A monoclonal antibody that reacts with a human Soluble fibrin but not with a
human fibrinogen; a hybridoma that Secretes the above antibody; and a method of assaying …

Reactivity of soluble fibrin assays with plasmic degradation products of fibrin and in patients receiving fibrinolytic therapy

BI McCarron, VJ Marder… - Thrombosis and …, 1999 - thieme-connect.com
The ability to identify the products of thrombin and plasmin action on fibrinogen is important
in patients with thrombotic and fibrinolytic disorders. New assays have been developed for …

Comparison of methods for detecting soluble fibrin in plasma. An in vitro study

S Halvorsen, OH Skjensberg, R Ruyter, HC Godal - Thrombosis research, 1990 - Elsevier
The ability of the COA-SET Fibrin monomer (COA-SET FM) test to detect soluble fibrin was
evaluated by comparing the results of the COA-SET FM test with fibrino-peptide A (FPA) …

Immunoassay and kit for in vitro detection of soluble DesAABB fibrin polymers

PE Gargan - US Patent 5,843,690, 1998 - Google Patents
An in vitro immunoassay to detect and quantitate soluble crosslinked and non-crosslinked
DesAABB? brin polymers in a sample from a subject. The assay can be used to support a …