Background/Aims Informed clinical guidance and health policy relies on clinicians,
policymakers, and guideline developers finding comprehensive clinical evidence and …

Background Studies measuring the completeness and consistency of trial registration and
reporting rely on linking registries with bibliographic databases. In this systematic review, we …

Objective Prospective registration has been widely implemented and accepted as a best
practice in clinical research, but retrospective registration is still commonly found. We …

Introduction Registration of clinical trials has been initiated in order to assess adherence of
the reported results to the original trial protocol. This study aimed to investigate the …

Introduction Analyses of clinical trial registries (CTRs) offer insights into methodological
problems of published research studies, eg, non-publication and outcome-switching. Here …

Context Since September 2005, the International Committee of Medical Journal Editors
(ICMJE) has required that randomised controlled trials (RCTs) are prospectively registered …

Objectives Trial registries can be used to measure reporting biases and support systematic
reviews, but 45% of registrations do not provide a link to the article reporting on the trial. We …

A substantial proportion of trial registrations are not linked to corresponding published
articles, limiting analyses and new tools. Our aim was to develop a method for finding …

Background Lack of transparency in clinical trial conduct, publication bias and selective
reporting bias are still important problems in medical research. Through clinical trials …

Introduction Clinical trial registries are an important source of information for tracking clinical
trials from their inception through to their reporting, and have been used to measure …