Tumor cells cannot grow as a mass above 2 to 3 mm3 because diffusion is insufficient for
oxygen and glucose requirements, unless the tumor induces a blood supply. This …

Angiogenesis is a key step in tumor growth, invasion and metastasis. Thus, antiangiogenic
therapy was postulated to be an attractive approach for antitumor treatment. Based on …

Angiogenesis, the development of a new blood supply, is an essential process of tumour
growth and metastasis. Over the past few years, this has led to the consideration of the …

Malignant tumours are angiogenesis-dependent diseases. Several experimental studies
suggest that primary tumour growth, invasiveness and metastasis require …

Inhibition of angiogenesis or preventing the outgrowth of new blood vessels towards a tumor
is one of the most promising areas of anticancer drug development. Several angiogenesis …

Angiogenesis—process of new blood-vessel growth from existing vasculature—is an
integral part of both normal developmental processes and numerous pathologies such as …

Advances in molecular biology have permitted the characterisation of mechanisms
underlying angiogenesis. Angiogenesis is a crucial process in tumour pathogenesis as it …

Angiogenesis is a complex process depending on the coordination of many regulators and
there by activating angiogenic switch. Recent advances in understanding of angiogenic …

Angiogenesis is the formation of new blood vessels from preexisting ones. Many solid
tumors depend on an extensive newly formed vascular network to become nourished and to …

Angiogenesis, the process of blood vessel formation, is crucial for malignant tumour growth
and metastases; therefore, it has become an attractive target for anticancer therapy …