The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

The increasing emergence and dissemination of multidrug resistant (MDR) bacterial
pathogens accelerate the desires for new antibiotics. Natural products dominate the …

Covering: up to November 2008New sources of antimicrobial products need to be identified
due to the existence and constant evolution of resistant microorganisms and phenotypes …

The discovery of antibiotics has revolutionized the medicine and treatment of microbial
infections. However, the current scenario has highlighted the difficulties in marketing new …

Introduction: Antimicrobial resistance is a worldwide problem accounting for the reduction or
in some cases absence of drugs effectiveness normally used in infections treatment. In the …

Antimicrobial resistance is considered a “One-Health” problem, impacting humans, animals,
and the environment. The problem of the rapid development and spread of bacteria resistant …

Drug efflux pumps confer resistance upon bacteria to a wide range of antibiotics from
various classes. The expression of efflux pumps are also implicated in virulence and biofilm …

Antibacterial drugs face increasing challenges due to drug resistance and adverse
reactions, which has created a pressing need for the discovery and development of novel …

Antibiotic resistance is becoming significantly prominent and urgent in clinical practice with
the increasing and wide application of antibacterial drugs. However, developing and …

Background There is urgent need to discover new antimicrobial compounds with diverse
chemical structures and mechanisms of action due to increasing new and re-emerging …