Resveratrol ameliorates dysregulation of Th1, Th2, Th17, and T regulatory cell-related transcription factor signaling in a BTBR T+ tf/J mouse model of autism

SA Bakheet, MZ Alzahrani, MA Ansari, A Nadeem… - Molecular …, 2017 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. It is characterized by
impaired social communication, abnormal social interactions, and repetitive behaviors …

Resveratrol Improves Neuroimmune Dysregulation Through the Inhibition of Neuronal Toll-Like Receptors and COX-2 Signaling in BTBR T+ Itpr3tf/J Mice

SF Ahmad, MA Ansari, A Nadeem, MZ Alzahrani… - Neuromolecular …, 2018 - Springer
Autism is a neurodevelopmental disorder characterized by deficits in qualitative impairments
in communication, repetitive and social interaction, restricted, and stereotyped patterns of …

Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T+ Itpr3tf/J autistic mice

SF Ahmad, MA Ansari, A Nadeem, SA Bakheet… - European journal of …, 2018 - Elsevier
Autism is a neurodevelopmental disorder characterized by qualitative impairment in
communication, social interaction, and repetitive stereotypic behavior. Resveratrol plays a …

Dysregulation of Th1, Th2, Th17, and T regulatory cell-related transcription factor signaling in children with autism

SF Ahmad, KMA Zoheir, MA Ansari, A Nadeem… - Molecular …, 2017 - Springer
Autism is a neurodevelopmental disorder characterized by stereotypic repetitive behaviors,
impaired social interactions, and communication deficits. Numerous immune system …

Resveratrol treatment attenuates chemokine receptor expression in the BTBR T+ tf/J mouse model of autism

SA Bakheet, MZ Alzahrani, A Nadeem… - Molecular and Cellular …, 2016 - Elsevier
Autism is a neurodevelopmental disorder categorized by qualitative impairments in social
interaction, communication, and repetitive stereotypic behavior. Emerging evidence …

Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in …

A Nadeem, SF Ahmad, NO Al-Harbi, SM Attia… - Behavioural brain …, 2019 - Elsevier
Autism is a neurodevelopmental disease which is characterized by its core behavioral
symptoms such as impairment in social interaction and stereotyped repetitive behavior …

Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

C Nicolini, Y Ahn, B Michalski, JM Rho… - Acta neuropathologica …, 2015 - Springer
Background The molecular mechanisms underlying autistic behaviors remain to be
elucidated. Mutations in genes linked to autism adversely affect molecules regulating …

The PPARδ agonist GW0742 restores neuroimmune function by regulating Tim-3 and Th17/Treg-related signaling in the BTBR autistic mouse model

SF Ahmad, A Nadeem, MA Ansari, SA Bakheet… - Neurochemistry …, 2018 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental disorders that are characterized
by repetitive behaviors, and impairments in communication and social interaction. Studies …

Resveratrol prevents social deficits in animal model of autism induced by valproic acid

V Bambini-Junior, G Zanatta, GDF Nunes… - Neuroscience …, 2014 - Elsevier
Autism spectrum disorders (ASD) involve a complex interplay of both genetic and
environmental risk factors, such as prenatal exposure to valproic acid (VPA). Considering …

Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/STAT pathway in the BTBR mouse model of autism

SF Ahmad, MA Ansari, A Nadeem, SA Bakheet… - Neurotoxicology, 2020 - Elsevier
Autism spectrum disorder (ASD) comprises a broad range of neurodevelopmental disorders
that are associated with deficits in social interaction and communication. The tyrosine kinase …