Background/Aims: Myoendothelial junctions (MEJs) represent a specialized signaling
domain between vascular smooth muscle cells (VSMC) and endothelial cells (EC). The …

The vascular endothelium is an important regulator of vascular reactivity and preserves the
balance between vasoconstrictor and vasodilator tone during normal physiologic conditions …

The role of gap junctions in endothelium-derived hyperpolarizing factor (EDHF)-mediated
relaxation of human arteries was assessed using connexin mimetic peptides (CMPs) …

Connexins have been hypothesized to play an important role in intercellular communication
within the vascular wall and may provide a mechanistic explanation for conduction of …

(1) The role of L-type Ca2+ channels in the relaxation to nitric oxide (NO)-mediated
MaxiKCa channel activation was examined in guinea pig aorta.(2) Acetylcholine (ACh) …

Although the chemical nature of endothelium-derived hyperpolarizing factor (EDHF) remains
elusive, electrophysiological evidence exists for electrical communication between smooth …

Cells rely on gap junctions for intercellular communication, which is important for growth and
contractility. For example, gap junctional communication in the uterus increases near …

Sodium fluoride was used to investigated a possible involvement of G-proteins in the
regulation of endothelial calcium channels. Incubation of cultured porcine aortic endothelial …

Objectives: Conduction of vasoconstrictor and vasodilator responses in the microcirculation
involves electrical coupling through gap junction channels among cells of the vascular wall …

Communication between cells is important to the microcirculation and enables the
coordination of cellular behavior along the length of the vessel. Arterioles span considerable …