Treatment of Acinetobacter Infections

J Fishbain, AY Peleg - Clinical infectious diseases, 2010 - academic.oup.com
Acinetobacter baumannii remains an important and difficult-to-treat pathogen whose
resistance patterns result in significant challenges for the clinician. Despite the prevalence …

MarA-mediated overexpression of the AcrAB efflux pump results in decreased susceptibility to tigecycline in Escherichia coli

D Keeney, A Ruzin, F McAleese… - Journal of …, 2008 - academic.oup.com
Objectives The purpose of this study was to characterize decreased susceptibility to
tigecycline in clinical isolates of Escherichia coli obtained during Phase 3 clinical trials …

A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline

NC Gordon, DW Wareham - Journal of antimicrobial …, 2009 - academic.oup.com
Abstract Objectives Multidrug-resistant Acinetobacter baumannii (MRAB) is an increasing
problem in UK hospitals, with many strains now resistant to all available antibiotics except …

[HTML][HTML] Global update on the in vitro activity of tigecycline and comparators against isolates of Acinetobacter baumannii and rates of resistant phenotypes (2016–2018 …

H Seifert, J Blondeau, K Lucassen, EA Utt - Journal of Global Antimicrobial …, 2022 - Elsevier
Objectives This study presents 2016–2018 in vitro antimicrobial activity data and rates of
resistant phenotypes for clinical isolates of Acinetobacter baumannii from Africa/Middle East …

Drug treatment for multidrug-resistant Acinetobacter baumannii infections

M Bassetti, E Righi, S Esposito, N Petrosillo, L Nicolini - 2008 - Future Medicine
Acinetobacter baumannii has emerged in the last decades as a major cause of healthcare-
associated infections and nosocomial outbreaks. Multidrug-resistant (MDR) A. baumannii is …

Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities

M Asif, IA Alvi, SU Rehman - Infection and drug resistance, 2018 - Taylor & Francis
Acinetobacter baumannii, once considered a low-category pathogen, has emerged as an
obstinate infectious agent. The scientific community is paying more attention to this …

[HTML][HTML] In vitro interactions of antibiotic combinations of colistin, tigecycline, and doripenem against extensively drug-resistant and multidrug-resistant Acinetobacter …

GC Park, JA Choi, SJ Jang, SH Jeong… - Annals of laboratory …, 2016 - ncbi.nlm.nih.gov
Background Acinetobacter baumannii infections are difficult to treat owing to the emergence
of various antibiotic resistant isolates. Because treatment options are limited for multidrug …

[HTML][HTML] Acinetobacter baumannii: evolution of antimicrobial resistance—treatment options

Y Doi, GL Murray, AY Peleg - Seminars in respiratory and …, 2015 - thieme-connect.com
The first decade of the 20th century witnessed a surge in the incidence of infections due to
several highly antimicrobial-resistant bacteria in hospitals worldwide. Acinetobacter …

Rapid Development of Acinetobacter baumannii Resistance to Tigecycline

GE Reid, SA Grim, CA Aldeza… - … : The Journal of …, 2007 - Wiley Online Library
A 53‐year‐old woman experienced a multidrug‐resistant (MDR) Acinetobacter baumannii
urinary tract infection 5 months after undergoing kidney and liver transplantation. The …

[HTML][HTML] In vitro effects of tigecycline in combination with colistin (polymyxin E) and sulbactam against multidrug-resistant Acinetobacter baumannii

W Ni, J Cui, B Liang, Y Cai, N Bai, X Cai… - The Journal of …, 2013 - nature.com
The lack of active antimicrobial agents against multidrug-resistant (MDR) Acinetobacter
baumannii has posed great threat to the public health. Combination therapies with …