Sulforaphane alleviates retinal ganglion cell death and inflammation by suppressing NLRP3 inflammasome activation in a rat model of retinal ischemia/reperfusion …
Y Gong, X Cao, L Gong, W Li - International Journal of …, 2019 - journals.sagepub.com
This study aims to study the potentials of sulforaphane (SFN) against retinal
ischemia/reperfusion (I/R) injury. A rat retinal I/R injury method was established. Retinal …
ischemia/reperfusion (I/R) injury. A rat retinal I/R injury method was established. Retinal …
Protective effects of sulforaphane on diabetic retinopathy: activation of the Nrf2 pathway and inhibition of NLRP3 inflammasome formation
S Li, H Yang, X Chen - Experimental Animals, 2019 - jstage.jst.go.jp
Sulforaphane (SFN) is abundant in cruciferous plants, providing significant protection
against many chronic diseases. With the aim of clarifying the efficacy of sulforaphane in …
against many chronic diseases. With the aim of clarifying the efficacy of sulforaphane in …
Sulforaphane modulates the inflammation and delays neurodegeneration on a retinitis pigmentosa mice model
A Canto, J Martínez-González, M Miranda… - Frontiers in …, 2022 - frontiersin.org
The term retinitis pigmentosa (RP) describes a large group of hereditary retinopathies. From
a cellular view, retinal degeneration is prompted by an initial death of rods, followed later by …
a cellular view, retinal degeneration is prompted by an initial death of rods, followed later by …
Sulforaphane protects rodent retinas against ischemia-reperfusion injury through the activation of the Nrf2/HO-1 antioxidant pathway
Retinal ischemia-reperfusion (I/R) injury induces oxidative stress, leukocyte infiltration, and
neuronal cell death. Sulforaphane (SF), which can be obtained in cruciferous vegetables …
neuronal cell death. Sulforaphane (SF), which can be obtained in cruciferous vegetables …
[HTML][HTML] Pioglitazone ameliorates retinal ischemia/reperfusion injury via suppressing NLRP3 inflammasome activities
YL Zhang, RB Wang, WY Li, FZ Xia… - International Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To explore the role of Pioglitazone (Pio) on a mouse model of retinal
ischemia/reperfusion (I/R) injury and to elucidate the potential mechanism. METHODS …
ischemia/reperfusion (I/R) injury and to elucidate the potential mechanism. METHODS …
[HTML][HTML] Roflumilast attenuates neuroinflammation post retinal ischemia/reperfusion injury by regulating microglia phenotype via the Nrf2/STING/NF-κB pathway
Y Guo, C Ou, N Zhang, Q Liu, K Xiong, J Yu… - International …, 2023 - Elsevier
Purpose The abnormal polarisation of microglial cells (MGs) following retinal
ischemia/reperfusion (RIR) initiates neuroinflammation and progressive death of retinal …
ischemia/reperfusion (RIR) initiates neuroinflammation and progressive death of retinal …
Puerarin ameliorates retinal ganglion cell damage induced by retinal ischemia/reperfusion through inhibiting the activation of TLR4/NLRP3 inflammasome
L Guan, C Li, Y Zhang, J Gong, G Wang, P Tian… - Life sciences, 2020 - Elsevier
Aims Retinal ischemia/reperfusion (I/R) injury is common in the development of ophthalmic
diseases and potentially causes blindness. In present study, the aim is to investigate the …
diseases and potentially causes blindness. In present study, the aim is to investigate the …
Sulforaphane improves outcomes and slows cerebral ischemic/reperfusion injury via inhibition of NLRP3 inflammasome activation in rats
C Yu, Q He, J Zheng, LY Li, YH Hou, FZ Song - International …, 2017 - Elsevier
Abstract Ischemia/reperfusion (I/R) injury has been correlated with systemic inflammatory
response. In addition, NLRP3 has been suggested as a cause in many inflammatory …
response. In addition, NLRP3 has been suggested as a cause in many inflammatory …
Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes
Y Qi, M Zhao, Y Bai, L Huang, W Yu… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Retinal ischemia/reperfusion (IR) is common in eye disorders. Pattern-recognition
receptors (PRRs) are reported to initiate sterile inflammatory response. The role of PRRs in …
receptors (PRRs) are reported to initiate sterile inflammatory response. The role of PRRs in …
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia–reperfusion rats via the tlr4/nf-κb/nlrp3 pathway
J Liu, N Zhang, M Zhang, H Yin, X Zhang… - Experimental Eye …, 2021 - Elsevier
This study aimed to explore the effects of N-acetylserotonin (NAS) on the expression of
interleukin-1β (IL-1β) in the retina of retinal ischemia–reperfusion injury (RIRI) rats via the …
interleukin-1β (IL-1β) in the retina of retinal ischemia–reperfusion injury (RIRI) rats via the …