A-1012G promoter polymorphism of vitamin D receptor gene is associated with psoriasis risk and lower allele-specific expression

AG Richetta, V Silvestri, S Giancristoforo… - DNA and Cell …, 2014 - liebertpub.com
Psoriasis is caused by a combination of genetic, immunologic, and environmental factors.
The vitamin D receptor (VDR) is involved in antiproliferative and prodifferentiation pathways …

Vitamin D receptor ApaI, TaqI, BsmI, and FokI polymorphisms and psoriasis susceptibility: an updated meta‐analysis

YH Lee - Clinical and experimental dermatology, 2019 - academic.oup.com
Background Vitamin D is considered a regulator of the immune system, and its
polymorphisms have been associated with psoriasis in some but not all reports. Aim To …

Vitamin D receptor ApaI, TaqI, BsmI, and FokI polymorphisms and psoriasis susceptibility: a meta-analysis

YH Lee, SJ Choi, JD Ji, GG Song - Molecular biology reports, 2012 - Springer
The aim of this study was to explore whether vitamin D receptor (VDR) polymorphisms
confer susceptibility to psoriasis. Meta-analyses were conducted on the associations …

[HTML][HTML] Vitamin D receptor gene polymorphism ApaI as a predisposing factor for psoriasis and its relation with serum vitamin D levels and psoriasis severity

G Alhetheli, MS Al-Dhubaibi, SS Bahaj, AI AbdElneam - Cureus, 2022 - ncbi.nlm.nih.gov
Abstract Background and Aim: Psoriasis is a chronic, relapsing and inflammatory
multisystemic disease with both genetic predisposition and autoimmune pathogenic traits …

Vitamin D receptor gene polymorphisms are associated with psoriasis susceptibility and the clinical response to calcipotriol in psoriatic patients

J Liu, W Wang, K Liu, D Wan, Z Wu… - Experimental …, 2020 - Wiley Online Library
Psoriasis is a common genetic disease characterized by hyperproliferation and disordered
maturation of keratinocytes. To date, many association studies between psoriasis and VDR …

Meta‐analysis of vitamin D receptor polymorphisms and psoriasis risk

M Stefanic, I Rucevic… - International journal of …, 2013 - Wiley Online Library
Summary Background Vitamin D receptor (VDR) gene polymorphisms have been studied as
candidate variants that affect psoriasis risk. However, results have been conflicting. Methods …

The association of polymorphisms of the vitamin D receptor gene with psoriasis in the Han population of northeastern China

X Zhou, L Xu, Y Li - Journal of Dermatological Science, 2014 - Elsevier
Background The vitamin D receptor (VDR) is a master regulator of epidermal barrier
function, inflammation, stem-cell proliferation, and microbial defense. Objective To evaluate …

[HTML][HTML] Vitamin D receptor polymorphism is associated with psoriasis

BS Park, DY Lee, JI Youn, JS Park, IG Kim - Journal of investigative …, 1999 - Elsevier
Vitamin D receptor is a trans-acting transcriptional factor that mediates 1α, 25-
dihydroxyvitamin D 3 action in the regulation of target gene expression. Recent studies have …

The vitamin D receptor gene polymorphism rs1544410 T/T genotype as a predictor of factor vitamin D thresholds deficiency in patients with psoriasis vulgaris—A …

AI AbdElneam, MS Al‐Dhubaibi… - Journal of Cosmetic …, 2023 - Wiley Online Library
Background Many clinical features of psoriasis include a rash with itchy, scaly patches, most
frequently on the knees, elbows, trunk, and scalp. By studying genes involved with psoriasis …

Lack of association of vitamin D receptor gene 3′‐haplotypes with psoriasis in Croatian patients

I Rucevic, M Stefanic, S Tokic, M Vuksic… - The Journal of …, 2012 - Wiley Online Library
Cis‐acting regulatory variants in biologically relevant pathways and target tissues are a
common source of phenotypic variations and individual disease susceptibility. In the skin …