[HTML][HTML] Evoked potentials reveal neural circuits engaged by human deep brain stimulation

SL Schmidt, DT Brocker, BD Swan, DA Turner, WM Grill - Brain stimulation, 2020 - Elsevier
Background Deep brain stimulation (DBS) is an effective therapy for reducing the motor
symptoms of Parkinson's disease, but the mechanisms of action of DBS and neural …

Stimulation of the subthalamic nucleus engages the cerebellum for motor function in parkinsonian rats

AC Sutton, KA O'Connor, JG Pilitsis… - Brain Structure and …, 2015 - Springer
Deep brain stimulation (DBS) is effective in managing motor symptoms of Parkinson's
disease in well-selected individuals. Recently, research has shown that DBS in the basal …

[HTML][HTML] Motor effects of deep brain stimulation correlate with increased functional connectivity in Parkinson's disease: An MEG study

LI Boon, A Hillebrand, WV Potters, RMA de Bie… - NeuroImage: Clinical, 2020 - Elsevier
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established
symptomatic treatment in Parkinson's disease, yet its mechanism of action is not fully …

Electrophysiologic evidence that directional deep brain stimulation activates distinct neural circuits in patients with Parkinson disease

J Peeters, A Boogers, T Van Bogaert, H Davidoff… - … : Technology at the …, 2023 - Elsevier
Objectives Deep brain stimulation (DBS) delivered via multicontact leads implanted in the
basal ganglia is an established therapy to treat Parkinson disease (PD). However, the …

The role of neurotransmitter systems in mediating deep brain stimulation effects in Parkinson's disease

F Alosaimi, JT Boonstra, S Tan, Y Temel… - Frontiers in …, 2022 - frontiersin.org
Deep brain stimulation (DBS) is among the most successful paradigms in both translational
and reverse translational neuroscience. DBS has developed into a standard treatment for …

Subthalamic neuromodulation improves short-term motor learning in Parkinson's disease

AL de Almeida Marcelino, A Horn, P Krause, AA Kühn… - Brain, 2019 - academic.oup.com
The basal ganglia and cerebellum are implicated in both motor learning and Parkinson's
disease. Deep brain stimulation (DBS) is an established treatment for advanced Parkinson's …

Model-based deconstruction of cortical evoked potentials generated by subthalamic nucleus deep brain stimulation

K Kumaravelu, CS Oza… - Journal of …, 2018 - journals.physiology.org
Parkinson's disease is associated with altered neural activity in the motor cortex. Chronic
high-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in …

Deep brain stimulation alleviates parkinsonian bradykinesia by regularizing pallidal activity

AD Dorval, AM Kuncel, MJ Birdno… - Journal of …, 2010 - journals.physiology.org
Deep brain stimulation (DBS) of the basal ganglia can alleviate the motor symptoms of
Parkinson's disease although the therapeutic mechanisms are unclear. We hypothesize that …

Subthalamic nucleus deep brain stimulation modulates 2 distinct neurocircuits

L Shen, C Jiang, CS Hubbard, J Ren, C He… - Annals of …, 2020 - Wiley Online Library
Objective Current understanding of the neuromodulatory effects of deep brain stimulation
(DBS) on large‐scale brain networks remains elusive, largely due to the lack of techniques …

Unilateral deep brain stimulation suppresses alpha and beta oscillations in sensorimotor cortices

O Abbasi, J Hirschmann, L Storzer, TE Özkurt, S Elben… - Neuroimage, 2018 - Elsevier
Deep brain stimulation (DBS) is an established therapy to treat motor symptoms in
movement disorders such as Parkinson's disease (PD). The mechanisms leading to the high …