Nobiletin prevents amyloid β1-40-induced cognitive impairment via inhibition of neuroinflammation and oxidative/nitrosative stress
R Ghasemi-Tarie, Z Kiasalari, M Fakour… - Metabolic Brain …, 2022 - Springer
Alzheimer's disease (AD) is presented as an age-related neurodegenerative disease with
multiple cognitive deficits and amyloid β (Aβ) accumulation is the most important involved …
multiple cognitive deficits and amyloid β (Aβ) accumulation is the most important involved …
[HTML][HTML] Discovery of nobiletin from citrus peel as a potent inhibitor of β-amyloid peptide toxicity
Increasing evidence has demonstrated that amyloid-β peptide (Aβ), the hallmark of
Alzheimer's disease (AD), evokes oxidative and inflammatory cascades, which ultimately …
Alzheimer's disease (AD), evokes oxidative and inflammatory cascades, which ultimately …
Nobiletin protects against systemic inflammation-stimulated memory impairment via MAPK and NF-κB signaling pathways
Neuroinflammation has been intensively demonstrated to be related to various
neurodegenerative diseases including Parkinson's disease (PD), amyotrophic lateral …
neurodegenerative diseases including Parkinson's disease (PD), amyotrophic lateral …
Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse
A Nakajima, Y Aoyama, TTL Nguyen, EJ Shin… - Behavioural Brain …, 2013 - Elsevier
Senescence-accelerated mouse prone 8 (SAMP8) is a model of aging characterized by the
early onset of learning and memory impairment and various pathological features of …
early onset of learning and memory impairment and various pathological features of …
[HTML][HTML] Nobiletin mitigates D-galactose-induced memory impairment via improving hippocampal neurogenesis in mice
W Xiong, R Li, B Li, X Wang, H Wang, Y Sun, X Wang… - Nutrients, 2023 - mdpi.com
Memory impairment is a characteristic of brain aging, and it is associated with a decrease in
neurogenesis. Therefore, enhancing neurogenesis is a potential method for mitigating brain …
neurogenesis. Therefore, enhancing neurogenesis is a potential method for mitigating brain …
[HTML][HTML] Anti-dementia activity of nobiletin, a citrus flavonoid: A review of animal studies
A Nakajima, Y Ohizumi, K Yamada - Clinical Psychopharmacology …, 2014 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), the most common form of dementia among the elderly, is
characterized by the progressive decline of cognitive function and has a detrimental impact …
characterized by the progressive decline of cognitive function and has a detrimental impact …
[HTML][HTML] Potential benefits of nobiletin, a citrus flavonoid, against Alzheimer's disease and Parkinson's disease
A Nakajima, Y Ohizumi - International journal of molecular sciences, 2019 - mdpi.com
Alzheimer's disease (AD), which is characterized by the presence of amyloid-β (Aβ) plaques
and neurofibrillary tangles, accompanied by neurodegeneration, is the most common form of …
and neurofibrillary tangles, accompanied by neurodegeneration, is the most common form of …
[HTML][HTML] Neuroprotective effect of Citrus unshiu immature peel and nobiletin inhibiting hydrogen peroxide-induced oxidative stress in HT22 murine hippocampal …
HW Cho, SY Jung, GH Lee, JH Cho… - Pharmacognosy …, 2015 - ncbi.nlm.nih.gov
Background: Oxidative stress-induced cell damage is common in the etiology of several
neurobiological disorders, including Alzheimer's disease and Parkinson's disease. In a case …
neurobiological disorders, including Alzheimer's disease and Parkinson's disease. In a case …
Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation
W Chai, J Zhang, Z Xiang, H Zhang, Z Mei, H Nie… - Metabolic brain …, 2022 - Springer
Objective This study aimed to explore the mechanism of Nobiletin attenuating Alzheimer's
disease (AD) by inhibiting neuroinflammation. Methods The expression of inflammatory …
disease (AD) by inhibiting neuroinflammation. Methods The expression of inflammatory …
[HTML][HTML] Neuroprotective effect of naringin against cerebellar changes in Alzheimer's disease through modulation of autophagy, oxidative stress and tau expression …
HM Hassan, MR Elnagar, E Abdelrazik… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by gradual
cognitive decline. Strong antioxidants that inhibit free radicals, such as polyphenols, reduce …
cognitive decline. Strong antioxidants that inhibit free radicals, such as polyphenols, reduce …
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