THE mechanisms responsible for development of inflammatory bowel disease (IBD) have
not been fully elucidated, although the main cause of disease pathology is attributed to up …

Anti‐inflammatory cytokines have an important role in disease, tumour and transplant
processes. Alterations in the regulation of several cytokines have been implicated in a …

Objective. Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory
diseases of the bowel, the causes of which are not fully known. Ethnic differences in disease …

METHODS Cytokine genotyping was performed utilizing polymerase chain reaction. The
specific gene polymorphisms that were probed for included:− 1082 (G/A),− 819 (T/C), and …

Abstract Objective Inflammatory bowel diseases (IBDs), namely ulcerative colitis (UC) and
Crohn's disease (CD), are characterized by chronic and idiopathic inflammatory conditions …

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that
genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The …

There is evidence of a disbalance in the inflammatory regulation of patients with
inflammatory bowel diseases (IBD). Interleukin-1β plays an important role in the pro …

Background The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative
colitis (UC), result from the combined effects of susceptibility genes and environmental …

Objective Research on inflammatory bowel disease (IBD) has highlighted genes involved in
the regulation of inflammatory responses as contributors to disease pathogenesis. This …

Inflammatory bowel disease (IBD) is a complex, multifactorial, chronic inflammatory disorder
of the gastrointestinal tract in which immune dysregulation caused by genetic and/or …