Well established for their central role in hemostasis, platelets have increasingly been
appreciated as immune cells in recent years. This emerging role should not come as a …

Although the function of platelets in the maintenance of hemostasis has been studied in
great detail, more recent evidence has highlighted a central role for platelets in the host …

A state-of-the-art lecture titled “novel mechanisms of thrombo-inflammation during infection”
was presented at the ISTH Congress in 2022. Platelet, neutrophil, and endothelial cell …

In addition to playing a central role in normal haemostasis, platelets make important
contributions to host inflammatory and immune responses to injury or infection. Under …

Thrombosis remains a major problem in our society, manifesting across multiple
demographic groups and with high associated morbidity and mortality. Thrombus …

Platelets are well characterized for their indispensable role in primary hemostasis to control
hemorrhage. Research over the past years has provided a substantial body of evidence …

The innate immune system orchestrated by leukocytes primarily neutrophils, serves to
remove dead and dying host cells and to provide protection against invasion by pathogens …

Sepsis is a severe illness caused by overwhelming infection of the bloodstream and affects
more than 750 000 people in the US each year [1]. The American College of Chest …

In addition to their well-known role as the cellular mediator of thrombosis, numerous studies
have identified key roles for platelets during various disease processes. Importantly …

Although platelets are traditionally recognized for their central role in hemostasis, many lines
of research clearly demonstrate these rather ubiquitous blood components are potent …