Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis

C Marti, G John, S Konstantinides… - European heart …, 2015 - academic.oup.com
Aim Thrombolytic therapy induces faster clot dissolution than anticoagulation in patients with
acute pulmonary embolism (PE) but is associated with an increased risk of haemorrhage …

Thrombolytic therapy of pulmonary embolism: a meta-analysis

G Thabut, D Thabut, RP Myers… - Journal of the American …, 2002 - jacc.org
Objectives: We sought to assess the efficacy and safety of thrombolytic therapy in patients
with an acute pulmonary embolism (PE). Background: Thrombolytic therapy is approved for …

Thrombolysis compared with heparin for the initial treatment of pulmonary embolism: a meta-analysis of the randomized controlled trials

S Wan, DJ Quinlan, G Agnelli, JW Eikelboom - Circulation, 2004 - Am Heart Assoc
Background—Randomized trials and meta-analyses have reached conflicting conclusions
about the role of thrombolytic therapy for the treatment of acute pulmonary embolism …

Thrombolytic therapy for acute pulmonary embolism: a critical appraisal

JL Todd, VF Tapson - Chest, 2009 - Elsevier
Pulmonary embolism is a prevalent condition that may account for> 300,000 deaths
annually in the United States alone. Although thrombolytics have been studied as a …

Thrombolysis vs heparin in the treatment of pulmonary embolism: a clinical outcome–based meta-analysis

G Agnelli, C Becattini, T Kirschstein - Archives of internal …, 2002 - jamanetwork.com
Background In patients with acute pulmonary embolism, thrombolysis results in a more rapid
resolution of pulmonary emboli than heparin treatment. Whether this advantage results in an …

[HTML][HTML] Thrombolytic therapy of pulmonary embolism: a comprehensive review of current evidence

SM Arcasoy, JW Kreit - Chest, 1999 - Elsevier
Pulmonary embolism (PE) is a common disorder that is accompanied by significant
morbidity and mortality. Although anticoagulation is the standard treatment for PE …

Thrombolytic therapy for pulmonary embolism

Q Hao, BR Dong, J Yue, T Wu… - Cochrane database of …, 2018 - cochranelibrary.com
Background Thrombolytic therapy is usually reserved for patients with clinically serious or
massive pulmonary embolism (PE). Evidence suggests that thrombolytic agents may …

Efficacy of thrombolytic agents in the treatment of pulmonary embolism

T Capstick, MT Henry - European Respiratory Journal, 2005 - Eur Respiratory Soc
Recent guidelines recommend bolus-dose alteplase for treating massive pulmonary
embolism (PE). However, the safest and most effective treatment is as yet unknown. In the …

Thrombolysis for pulmonary embolism and risk of all-cause mortality, major bleeding, and intracranial hemorrhage: a meta-analysis

S Chatterjee, A Chakraborty, I Weinberg, M Kadakia… - Jama, 2014 - jamanetwork.com
Importance Thrombolytic therapy may be beneficial in the treatment of some patients with
pulmonary embolism. To date, no analysis has had adequate statistical power to determine …

Association between thrombolytic treatment and the prognosis of hemodynamically stable patients with major pulmonary embolism: results of a multicenter registry

S Konstantinides, A Geibel, M Olschewski, F Heinrich… - Circulation, 1997 - Am Heart Assoc
Background Thrombolytic treatment has been shown to accelerate resolution of major
pulmonary embolism and lead to a rapid improvement of right-side hemodynamics …