Obesity-prone (OP) rodents are used as models of human obesity predisposition. The goal
of the present study was to identify preexisting defects in energy expenditure components in …

While most rats gain weight when placed on a high-fat diet (HFD), some strains resist HFD-
induced weight gain. To maintain weight, obesity-resistant (OR) rats must either eat less …

Obesity results from positive energy balance and, perhaps, abnormalities in lipid and
glycogen metabolism. The purpose of this study was to determine whether differences in …

We compared, across several physiological variables, rats most and least susceptible to
develop obesity when given a high-fat diet. After 4 wk of eating a high-fat diet (60% of …

The purpose of the current study was to examine the enzymatic profile [phosphofructokinase
(PFK), beta-hydroxyacyl-CoA dehydrogenase (HADH), and citrate synthase (CS)] in …

High fat feeding in rodents generally leads to obesity and insulin resistance whereas in
humans this is only seen if dietary carbohydrate is also high, the result of the anabolic effect …

Caloric restriction (CR) and metabolic glucoprivation affect spontaneous physical activity
(SPA), but it's unknown whether these treatments similarly affect SPA in selectively bred …

Objective: Childhood obesity is an emerging health problem. This study assesses the effects
of three levels of dietary fat (10%, 32%, and 45% measured by kilocalories) on weight gain …

Obesity is reaching epidemic proportions and predisposes afflicted individuals to several
comorbidities. For these individuals, losing weight has proven to be an easier feat than …

Rats prone to develop diet-induced obesity (DIO) have reduced central sensitivity to many
metabolic and hormonal signals involved in energy homeostasis. High-fat diets produce …