Circulating cytokines in sarcoidosis: phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease
KC Patterson, BS Franek, J Müller-Quernheim… - Cytokine, 2013 - Elsevier
AIMS: Sarcoidosis is a granulomatous disease of unknown etiology marked by tremendous
clinical heterogeneity. Many patients enter remission with good long-term outcomes. Yet …
clinical heterogeneity. Many patients enter remission with good long-term outcomes. Yet …
The clinical and immunologic features of pulmonary fibrosis in sarcoidosis
KC Patterson, K Hogarth, AN Husain, AI Sperling… - Translational …, 2012 - Elsevier
Sarcoidosis is a multisystem, granulomatous disease that most often affects the lungs. The
clinical course is highly variable; many patients undergo spontaneous remission, but up to a …
clinical course is highly variable; many patients undergo spontaneous remission, but up to a …
Inflammatory pathways in sarcoidosis
BP Barna, MA Judson, MJ Thomassen - … in Health and Disease, Volume II, 2021 - Springer
Abstract Concepts regarding etiology and pathophysiology of sarcoidosis have changed
remarkably within the past 5 years. Sarcoidosis is now viewed as a complex multi-causation …
remarkably within the past 5 years. Sarcoidosis is now viewed as a complex multi-causation …
The immunology of sarcoidosis
AK Gerke, G Hunninghake - Clinics in chest medicine, 2008 - Elsevier
Sarcoidosis continues to be a disease of research interest because of its complicated
immune mechanisms and elusive etiology. So far, it has been established that …
immune mechanisms and elusive etiology. So far, it has been established that …
Immune mechanisms in fibrotic pulmonary sarcoidosis
P Weeratunga, DR Moller, LP Ho - European Respiratory …, 2022 - Eur Respiratory Soc
Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily
mapped out over the past few decades. Despite this, the underpinning mechanisms for …
mapped out over the past few decades. Despite this, the underpinning mechanisms for …
Immunologic response of sarcoidosis
Sarcoidosis is a chronic granulomatous disorder characterized by an accumulation of T
lymphocytes, macrophages, and immune-effector cells within affected organs. The …
lymphocytes, macrophages, and immune-effector cells within affected organs. The …
Immunology of sarcoidosis: old companions, new relationships
Evidence points at microenvironment and cell functional features rather than cell
polarization or differentiation as determinants of pathogenesis. In terms of therapeutic …
polarization or differentiation as determinants of pathogenesis. In terms of therapeutic …
Cells and cytokines involved in the pathogenesis of sarcoidosis.
DR Moller - Sarcoidosis, Vasculitis, and Diffuse Lung Diseases …, 1999 - europepmc.org
Granulomatous inflammation develops under the regulatory influence of cytokines produced
by local mononuclear phagocytes, T cells, dendritic cells, fibroblasts, and other local cells. In …
by local mononuclear phagocytes, T cells, dendritic cells, fibroblasts, and other local cells. In …
Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis.
DR Moller, JD Forman, MC Liu, PW Noble… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by
the expansion of activated oligoclonal CD4+ T cells and macrophages at sites of disease. To …
the expansion of activated oligoclonal CD4+ T cells and macrophages at sites of disease. To …
The pathogenesis of pulmonary sarcoidosis and implications for treatment
KC Patterson, ES Chen - Chest, 2018 - Elsevier
Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …
heterogeneous group of patients with a wide range of clinical features and associated …