Background Multiple sclerosis (MS), an autoimmune disease of the central nervous system
(CNS), can be suppressed in its early stages but eventually becomes clinically progressive …

Multiple sclerosis (MS) is a chronic inflammatory disease mediated by a complex interaction
between the autoreactive lymphocytes and the effector myeloid cells within the central …

Objective To identify an MS-specific immune cell population by deep immune phenotyping
and relate it to soluble signaling molecules in CSF. Methods We analyzed surface …

Neutrophils and monocytes encompassing the classical, intermediate, and nonclassical
population constitute the majority of circulating myeloid cells in humans and represent the …

One of the biggest challenges in managing multiple sclerosis is the heterogeneity of clinical
manifestations and progression trajectories. It still remains to be elucidated whether this …

Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous
system (CNS). Bone marrow hematopoietic stem and progenitor cells (HSPCs) rapidly …

Multiple sclerosis (MS) is an inflammatory demyelinating disease characterised by immune
abnormalities in the central nervous system (CNS) as well as systemically. Activated, blood …

Multiple sclerosis (MS) is an immune mediated, inflammatory and demyelinating disease of
the central nervous system (CNS). Substantial evidence points toward monocytes and …

Multiple sclerosis (MS) is a chronic, autoimmune, and neurodegenerative disease of the
central nervous system (CNS) that affects myelin. The etiology of MS is unclear, although a …

Objective In multiple sclerosis (MS), central nervous system (CNS), cerebrospinal fluid
(CSF), and blood display TCR clonal expansions of CD 8+ T cells. These clones have been …