Multiple sclerosis (MS) is an inflammatory demyelinating and degenerative disease of the
central nervous system (CNS). Although inflammatory responses are efficiently treated …

A role of B cells in multiple sclerosis (MS) is well established, but there is limited
understanding of their involvement during active disease. Here, we examined cerebrospinal …

Peripheral blood mononuclear cells (PBMCs) bear specific dysregulations in genes and
pathways at distinct stages of multiple sclerosis (MS) that may help with classifying MS and …

Multiple Sclerosis (MS) is the second cause of paraplegia among young adults, after all
types of CNS traumatic lesions. In its most frequent relapsing-remitting form, the severity of …

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the myelination of the
neurons present in the central nervous system (CNS). The exact etiology of MS development …

Specialized populations of tissue-resident myeloid cells inhabit every organ of the body.
While many of these populations appear similar morphologically and phenotypically, they …

Monocytes represent a heterogeneous population of primary immune effector cells. At least
three different subsets can be distinguished based on expression of the low-affinity FcγRIII …

Objective The management of complex patients with neuroimmunological diseases is
hindered by an inability to reliably measure intrathecal inflammation. Currently implemented …

Multiple sclerosis (MS) is a chronic disease that is characterized by the inappropriate
invasion of lymphocytes and monocytes into the central nervous system (CNS), where they …

Background Plasmacytoid dendritic cells have been implicated in the pathogenesis of
systemic sclerosis through mechanisms beyond the previously suggested production of type …