Drug-drug interactions (DDIs) among widely and chronically prescribed medications are a
relevant health issue in clinical practice. Reported incidences in outpatients range from …

Cardiovascular morbidity is the leading cause of mortality in the developed nations.
Elevated serum cholesterol is a major risk factor for ischemic heart disease, one of the …

Elderly patients are a special category of patients, due to the physiological changes induced
by age, the great number of comorbidities and drug treatment and last, but not least, to the …

Australia's oldest old are potentially being harmed by the under-and over-use of statins.
Variations in prescription of statins are in part due to the vacuum of clinical research trial …

Atherosclerosis is a progressive, lifelong condition that is the leading cause of death among
middle-aged and elderly individuals aged≥ 65 years. Up to 80% of elderly patients are …

Atherosclerotic cardiovascular diseases (ASCVD) are the leading cause of death worldwide.
High levels of total cholesterol—and of low-density lipoprotein cholesterol in particular—are …

Statins have proven benefit in the elderly in those with coronary heart disease and diabetes
mellitus. Future studies exploring statin efficacy in primary prevention for patients older than …

Although elderly patients represent a rapidly growing population often requiring multiple
drug treatment, the evidence of effectiveness is limited for many interventions and therapies …

Background—Although statins reduce the risk of cardiovascular events, concerns about
adverse effects may deter physicians from prescribing these agents. We performed a …

Background. Cardiovascular disease is the principal cause of mortality in older individuals,
and more than 80% of deaths due to coronary heart disease or stroke occur in patients over …