Efficacy of statin treatment based on cardiovascular outcomes in elderly patients: a standard meta-analysis and Bayesian network analysis

C Zhai, K Hou, R Li, YC Hu, JX Zhang… - Journal of …, 2020 - journals.sagepub.com
Objective Statins have been shown to be beneficial for the prevention of cardiovascular
events. In elderly individuals, the efficacy of statins remains controversial and the …

[HTML][HTML] Choosing statins: a review to guide clinical practice

RP Borges, NAH Degobi, MC Bertoluci - Archives of Endocrinology …, 2020 - SciELO Brasil
Statins are among the most widely prescribed medicines in the world and have proved their
value in reducing cardiovascular events and mortality. Many patients report adverse effects …

How well tolerated are lipid-lowering drugs?

B Tomlinson, P Chan, W Lan - Drugs & aging, 2001 - Springer
It has been clearly established that lipid-lowering treatments [such as 3-hydroxyl-3-
methylglutamyl coenzyme A reductase inhibitors ('statins') or fibrates] can reduce …

Safety of statins: focus on clinical pharmacokinetics and drug interactions

S Bellosta, R Paoletti, A Corsini - Circulation, 2004 - Am Heart Assoc
Statin monotherapy is generally well tolerated, with a low frequency of adverse events. The
most important adverse effects associated with statins are myopathy and an asymptomatic …

Lipid management in the geriatric patient

AP Nair, B Darrow - Endocrinology and metabolism clinics of North America, 2009 - Elsevier
Elderly individuals are at higher risk for cardiovascular events, and thus this population
stands to gain a greater reduction in events from lipid therapy than younger individuals …

Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence

R Ali, KP Alexander - The American Journal of Geriatric Pharmacotherapy, 2007 - Elsevier
BACKGROUND:: Although statins have been demonstrated to be beneficial for secondary
prevention in the elderly, their use for primary prevention has not been well described …

Drug interactions of the statins and consequences for drug selection.

RH Böger - International journal of clinical pharmacology and …, 2001 - europepmc.org
Cholesterol-lowering drugs such as HMG-CoA reductase inhibitors (" statins") are
increasingly used in hypercholesterolemic patients who suffer from multiple concomitant …

Statins for the primary prevention of cardiovascular disease in the elderly

RN Lowe, JP Vande Griend… - The Consultant …, 2015 - ingentaconnect.com
Objective: The objective is to review the evidence evaluating the efficacy of statin therapy for
primary prevention of cardiovascular (CV) disease in the elderly. Data Sources: A literature …

[HTML][HTML] Selective serotonin reuptake inhibitor drug interactions in patients receiving statins

C Andrade - The Journal of clinical psychiatry, 2014 - legacy.psychiatrist.com
Elderly patients commonly receive statin drugs for the primary or secondary prevention of
cardiovascular and cerebrovascular events. Elderly patients also commonly receive …

The care gap: underuse of statin therapy in the elderly

A Gaw - International journal of clinical practice, 2004 - Wiley Online Library
Atherosclerotic diseases are responsible for the majority of deaths in the elderly, and they
can also increase the risk of disability. Statins are first‐line therapies for lowering lipid levels …