The distributed genome hypothesis (DGH) states that each strain within a bacterial species
receives a unique distribution of genes from a population-based supragenome that is many …

Genome analyses have documented that there are differences in gene repertoire between
evolutionary distant lineages of the same bacterial species; however, less is known about …

One of the hallmarks of the Gram-negative bacterium Pseudomonas aeruginosa is its ability
to thrive in diverse environments that includes humans with a variety of debilitating diseases …

The opportunistic pathogen Pseudomonas aeruginosa causes serious infections in
immunocompromised patients and individuals with cystic fibrosis (CF). It is one of the most …

ABSTRACT The Gram-negative bacterium Pseudomonas aeruginosa is a common cause of
chronic airway infections in individuals with the heritable disease cystic fibrosis (CF). After …

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lungs of
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …

The comparative genomics of the transition of the opportunistic pathogen Pseudomonas
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …

Genome sequencing of bacterial pathogens has advanced our understanding of their
evolution, epidemiology, and response to antibiotic therapy. However, we still have only a …

Pseudomonas aeruginosa chronically colonizing the lungs of cystic fibrosis (CF) patients
undergoes fast evolution leading to clonal divergence. More than half of the genotypes of P …

How biodiversity arises and can be maintained in asexual microbial populations growing on
a single resource remains unclear. Many models presume that beneficial genotypes will …