Patients with the same neuropathic pain disorder may have completely different sensory
signs and symptoms yet receive the same medicinal treatment. New concepts suggest that …

The discussed trials show the importance of the development of an individualized pain
therapy. Up to now, no clinical trial has prospectively used the sensory phenotype as an …

Patients with the same disease may suffer from completely different pain symptoms yet
receive the same drug treatment. Several studies elucidate neuropathic pain and treatment …

Unlike the plethora of drugs available to treat epilepsy, depression, or migraine,
comparatively few and insufficiently effective drugs are available for neuropathic pain …

The drugs available for treatment of neuropathic pain have somewhat disappointing efficacy
with many patients left with limited or no effect. Individualized treatment based on phenotype …

Background The treatment of neuropathic pain remains a major unmet need that the
development of personalized and refined treatment strategies may contribute to address …

The personalization of neuropathic pain treatment could be improved by identifying specific
sensory phenotypes (ie, specific combinations of symptoms and signs) predictive of the …

Classification of neuropathic pain has been based on disease entities, anatomical
localization, or histological observations. Over the past decade, there has been an explosion …

Abstract Treatment of neuropathic pain remains inadequate despite the elucidation of
multiple pathophysiological mechanisms and the development of promising therapeutic …

Neuropathic pain syndromes, ie, pain after a lesion or disease of the peripheral or central
nervous system, are clinically characterized by spontaneous pain (ongoing, paroxysms) and …