Systematic profiling of immune signatures identifies prognostic predictors in lung adenocarcinoma

S Mao, Y Li, Z Lu, Y Che, J Huang, Y Lei, Y Wang… - Cellular Oncology, 2020 - Springer
Purpose Lung adenocarcinoma (LUAD) is the predominant subtype of lung cancer, with
increasing evidence showing clinical benefits of immunotherapy. However, a lack of …

[HTML][HTML] A novel immune-related prognostic model for response to immunotherapy and survival in patients with lung adenocarcinoma

Y Zheng, H Tian, Z Zhou, C Xiao, H Liu, Y Liu… - Frontiers in Cell and …, 2021 - frontiersin.org
Lung adenocarcinoma is one of the most malignant diseases worldwide. The immune
checkpoint inhibitors targeting programmed cell death protein 1 (PD-1) and programmed …

[HTML][HTML] Identification of an immune signature predicting prognosis risk of patients in lung adenocarcinoma

Q Song, J Shang, Z Yang, L Zhang, C Zhang… - Journal of translational …, 2019 - Springer
Background Lung cancer has become the most common cancer type and caused the most
cancer deaths. Lung adenocarcinoma (LUAD) is one of the major type of lung cancer. This …

Development and validation of an immune‐related prognostic signature in lung adenocarcinoma

S Sun, W Guo, Z Wang, X Wang, G Zhang… - Cancer …, 2020 - Wiley Online Library
Background Lung adenocarcinomas (LUAD) is the most common histological subtype of
lung cancers. Tumor immune microenvironment (TIME) is involved in tumorigeneses …

[HTML][HTML] Development and validation of a 12-gene immune relevant prognostic signature for lung adenocarcinoma through machine learning strategies

L Xue, G Bi, C Zhan, Y Zhang, Y Yuan, H Fan - Frontiers in oncology, 2020 - frontiersin.org
Background: Although immunotherapy with checkpoint inhibitors is changing the face of
lung adenocarcinoma (LUAD) treatments, only limited patients could benefit from it …

[HTML][HTML] Leveraging an immune cell signature to improve the survival and immunotherapy response of lung adenocarcinoma

J Zhang, T Kuang, K Dong, J Yu, W Wang - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Background: Immune cells play a critical role in the prognosis of cancer. However, the
function of different immune cell types in lung adenocarcinoma (LUAD) and the …

[HTML][HTML] Identification of immune activation-related gene signature for predicting prognosis and immunotherapy efficacy in lung adenocarcinoma

W Zeng, J Wang, J Yang, Z Chen, Y Cui, Q Li… - Frontiers in …, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a major subtype of non-small cell lung cancer
(NSCLC) with a highly heterogeneous tumor microenvironment. Immune checkpoint …

Systematic construction and validation of an immune prognostic model for lung adenocarcinoma

C Luo, M Lei, Y Zhang, Q Zhang, L Li… - Journal of Cellular …, 2020 - Wiley Online Library
Lung adenocarcinoma (LUAD), the most common non‐small‐cell lung cancer, is
characterized by a dense lymphocytic infiltrate, which indicates that the immune system …

A gene expression-based immune signature for lung adenocarcinoma prognosis

L Wang, X Luo, C Cheng, CI Amos, G Cai… - Cancer Immunology …, 2020 - Springer
Background Lung adenocarcinoma (LUAD) has become the most frequent histologic type of
lung cancer in the past several decades. Recent successes with immune checkpoint …

[HTML][HTML] Comprehensive analysis and identification of subtypes and hub genes of high immune response in lung adenocarcinoma

H Li, Y Lei, X Lai, R Huang, Y Xiang, Z Zhao… - BMC Pulmonary …, 2024 - Springer
Background The advent of immunotherapy targeting immune checkpoints has conferred
significant clinical advantages to patients with lung adenocarcinoma (LUAD); However, only …