[HTML][HTML] RNA-Seq identifies marked Th17 cell activation and altered CFTR expression in different atopic dermatitis subtypes in Chinese Han populations
X Tian, B Liu, L Chen, Y Xie, J Liang, Y Yang… - Frontiers in …, 2021 - frontiersin.org
Background Patients with atopic dermatitis (AD) exhibit phenotypic variability in ethnicity and
IgE status. In addition, some patients develop other allergic conditions, such as allergic …
IgE status. In addition, some patients develop other allergic conditions, such as allergic …
Single‐cell RNA‐seq reveals abnormal differentiation of keratinocytes and increased inflammatory differentiated keratinocytes in atopic dermatitis
J Zhou, G Liang, L Liu, S Feng, Z Zheng… - Journal of the …, 2023 - Wiley Online Library
Background Atopic dermatitis (AD) is a chronic and recurrent inflammatory skin disease
characterized by severe pruritus and eczematous lesions. Heterogeneity of AD has been …
characterized by severe pruritus and eczematous lesions. Heterogeneity of AD has been …
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization
Background Atopic dermatitis (AD) shows very high prevalence in Asia, with a large unmet
need for effective therapeutics. Direct comparisons between European American (EA) and …
need for effective therapeutics. Direct comparisons between European American (EA) and …
Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation
RD Sanyal, AB Pavel, J Glickman, TC Chan… - Annals of Allergy …, 2019 - Elsevier
Abstract Background African Americans (AA) are disproportionately impacted by atopic
dermatitis (AD), with increased prevalence and therapeutic challenges unique to this …
dermatitis (AD), with increased prevalence and therapeutic challenges unique to this …
[HTML][HTML] Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation
Atopic dermatitis (AD) often presents more severely in African Americans (AAs) and with
greater involvement of extensor areas. To investigate immune signatures of AD in AAs with …
greater involvement of extensor areas. To investigate immune signatures of AD in AAs with …
Single‐cell profiles reveal distinctive immune response in atopic dermatitis in contrast to psoriasis
B Zhang, LM Roesner, S Traidl, VACM Koeken, CJ Xu… - Allergy, 2023 - Wiley Online Library
Background Understanding the complex orchestrated inflammation in atopic dermatitis (AD),
one of the most common chronic inflammatory diseases worldwide, is essential for …
one of the most common chronic inflammatory diseases worldwide, is essential for …
Multipolarity of cytokine axes in the pathogenesis of atopic dermatitis in terms of age, race, species, disease stage and biomarkers
T Nomura, T Honda, K Kabashima - International immunology, 2018 - academic.oup.com
Atopic dermatitis (AD) is a common T-cell-mediated inflammatory disease of the skin.
Signatures of AD are characterized by an impaired skin barrier, aberrant Th2-type cytokine …
Signatures of AD are characterized by an impaired skin barrier, aberrant Th2-type cytokine …
Possible role of Th17 cells and IL-17 in the pathogenesis of atopic dermatitis in northern China
L Ma, HB Xue, XH Guan, RQ Qi, RZ An… - Journal of …, 2012 - jdsjournal.com
Atopic dermatitis (AD) is a common, chronic relapsing, inflammatory skin disease, which is
usually associated with other systemic atopic disorders such as allergic asthma and rhinitis …
usually associated with other systemic atopic disorders such as allergic asthma and rhinitis …
RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications
Background Genomic profiling of lesional and nonlesional skin of patients with atopic
dermatitis (AD) using microarrays has led to increased understanding of AD and …
dermatitis (AD) using microarrays has led to increased understanding of AD and …
[HTML][HTML] Atopic dermatitis is an IL-13–dominant disease with greater molecular heterogeneity compared to psoriasis
LC Tsoi, E Rodriguez, F Degenhardt, H Baurecht… - Journal of Investigative …, 2019 - Elsevier
Atopic dermatitis (AD) affects up to 20% of children and adults worldwide. To gain a deeper
understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic …
understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic …
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